05 September 2022 : Clinical Research
Interaction of High-Sugar Diet and History of Stroke with Risk of Cognitive Decline in Older Adults
Qian Xu1AEFG, Sicong Zhang2BCD, Yanqing Gu1C, Ping Wang1D, Qian Zhang1B, Chunlei Shan234AEG*DOI: 10.12659/MSM.937572
Med Sci Monit 2022; 28:e937572
Table 2 The associations of history of stroke or high-sugar diet with cognitive decline.
| Variable | Model 1 | Model 2 | Model 3 | |||
|---|---|---|---|---|---|---|
| OR (95% CI) | P | OR (95% CI) | P | OR (95% CI) | P | |
| History of stroke | ||||||
| No | Ref | Ref | ||||
| Yes | 2.469 (1.592–3.830) | <0.001 | 2.151 (1.428–3.240) | 0.001 | 1.826 (1.124–2.968) | 0.017 |
| Content of added sugar | ||||||
| Normal | Ref | Ref | Ref | |||
| High level | 1.667 (1.285–2.164) | <0.001 | 1.864 (1.418–2.451) | <0.001 | 1.509 (1.109–2.052) | 0.010 |
| Unadjusted univariate logistic analysis; Multivariable logistic analysis adjusted for age, gender, diabetes and GHb; Multivariable logistic analysis adjusted for age, gender, diabetes, GHb, BMI, race, marital status, education, family income, drinking, vigorous work activity, vigorous recreational activities, depression disorder, hypertension, congestive heart failure, heart disease, TC and HDL. OR – odds ratio; CI – confidence interval. | ||||||