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30 September 2022: Clinical Research

Effects of Left Atrial Appendage Closure on Neuroendocrine Function in Patients with Nonvalvular Atrial Fibrillation

Fei Wang ABE , Zhong-bao Ruan BDG* , Ge-cai Chen BC , Jun-guo Zhu CF , Li Zhu A

DOI: 10.12659/MSM.937586

Med Sci Monit 2022; 28:e937586

Table 1 Baseline characteristics of the included patients.

Baseline characteristics (n=20)
Age, years69.35±8.29
Female, n (%)4 (20%)
Body mass index, kg/m24.78±3.14
Coronary artery disease6 (30%)
Hypertension, n (%)11 (55%)
Diabetes mellitus, n (%)5 (25%)
Stroke/TIA/thromboembolism, n (%)7 (35%)
Vascular disease, n (%)12 (60%)
Congestive heart failure, n (%)5 (25%)
Abnormal liver function, n (%)1 (5%)
Abnormal renal function, n (%)3 (15%)
Labile INRs, n (%)6 (30%)
Alcohol, n (%)2 (10%)
CHADS-VASc3.00±1.45
HAS-BLED2.52±0.89
NVAF type
 Paroxysmal atrial fibrillation, n (%)3 (15%)
 Persistent atrial fibrillation, n (%)17 (85%)
Left ventricular ejection fraction, %60.95±11.6
Left atrial size, mm49.05±7.07
Medicine drugs
 Angiotensin-converting enzyme inhibitors6 (30%)
 Angiotonin receptor blockers7 (35%)
 Aldosterone antagonists4 (20%)
 Beta-blockers7 (35%)

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750