19 October 2022: Review Articles
A Review of the Role of Ultrasound Radiomics and Its Application and Limitations in the Investigation of Thyroid Disease
Wen-Wu Lu 1E , Di Zhang 2F , Xue-Jun Ni 1E*DOI: 10.12659/MSM.937738
Med Sci Monit 2022; 28:e937738
Table 1 Application of ultrasound radiomics in thyroid imaging.
| Reference | Task | No. of patients | Method | Results |
|---|---|---|---|---|
| Liang et al, []36 | Predicting malignancy in thyroid nodules | 232 | ML-based radiomics | External test set AUC: 0.931 |
| Luo et al, []37 | Discriminating benign and malignant thyroid nodules | 394 | ML-based radiomics and Logistic | Combined model in test set AUC: 0.913 |
| Wu et al, []40 | Improve the differential diagnosis of thyroid nodules | 1396 | DL-based radiomics | AUCs: 0.904 on TR4; 0.845 on TR5; 0.829 on TR4&5 |
| Zhao et al, []43 | Diagnostic performance and unnecessary biopsy rate | 822 | ML-based radiomics | Combined with SWE model in external test set AUC: 0.953 |
| Wang et al, []45 | Evaluation of extrathyroidal extension in PTC | 161 | ML-based radiomics and Logistic | Test set AUC: 0.824 |
| Xia et al, []46 | Prediction of lymph node metastasis in patients with PTC | 445 | SVM and PNN | Test score of SVM: 0.93; Test score of PNN: 0.88 |
| Jiang et al, []23 | SWE radiomics improve preoperative cervical lymph node staging for PTC | 237 | ML-based radiomics and Logistic | Combined model in external test set AUC: 0.832 |
| Wang et al, []51 | Predicting BRAF V600E mutations in PTC | 138 | ML-based radiomics | Elasticity and grayscale ultrasound radiomic model in test set AUC: 0.938 |
| Park et al, []54 | Association between radiomics signature and disease-free survival in PTC | 768 | ML-based radiomics and COX regression | C-index of the ultrasound radiomic model: 0.777; C-index of the clinicopathologic model: 0.721 |
| ML – machine learning; DL – deep learning; AUC – area under curve; TR – thyroid imaging, reporting and data system; PTC – papillary thyroid carcinoma; SWE – shear wave elastography; SVM – support vector machines; PNN – probabilistic neural network. | ||||