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14 October 2022: Clinical Research

Correlation Between Trough Level of Abiraterone and Prostate-Specific Antigen (PSA) Response in Metastatic Hormone-Sensitive Prostate Cancer

Zin W. Myint 12ABCDEFG* , Jill M. Kolesar 23CDE , Joseph Robert McCorkle 2CDE , Jianrong Wu 4C , Carleton S. Ellis 23CDE , Danielle E. Otto 23CDE , Peng Wang 12ACDE

DOI: 10.12659/MSM.938091

Med Sci Monit 2022; 28:e938091

Table 4 Correlation between 1-month, 3-month, and 7-month abiraterone trough levels and prostate-specific antigen levels stratified by obesity vs non-obesity.

Correlation (PSA, AA)Spearman rank correlationP valueSpearman correlationP value
Obese (BMI >30)Non-obese (BMI <30)
1 Month0.20.70.20000.75
3 Months−0.70.19−0.60000.40
7 Months−0.001.0
BMI – body mass index, PSA – prostate-specific antigen; AA – abiraterone acetate.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750