Correlation Between Trough Level of Abiraterone and Prostate-Specific Antigen (PSA) Response in Metastatic Hormone-Sensitive Prostate Cancer

Zin W. Myint; Jill M. Kolesar; Joseph Robert McCorkle; Jianrong Wu; Carleton S. Ellis; Danielle E. Otto; Peng Wang

doi:10.12659/MSM.938091

14 October 2022 : Clinical Research

Correlation Between Trough Level of Abiraterone and Prostate-Specific Antigen (PSA) Response in Metastatic Hormone-Sensitive Prostate Cancer

Zin W. Myint^12ABCDEFG*, Jill M. Kolesar^23CDE, Joseph Robert McCorkle^2CDE, Jianrong Wu^4C, Carleton S. Ellis^32CDE, Danielle E. Otto^23CDE, Peng Wang^12ACDE

DOI: 10.12659/MSM.938091

Med Sci Monit 2022; 28:e938091

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Table 8 Association between HSD3B1 genotype risk-allele and survival outcomes (overall survival and response).

	Risk allele		P value

	Yes	No

Alive
Yes	4	35	0.79
No	2	1

Survival response
Yes (CR, PR)	2	3	0.22
No (SD, PD)	4	1
OS – overall survival; CR – complete response; PR – partial response; SD – stable disease; PD – progressive disease.

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Correlation Between Trough Level of Abiraterone and Prostate-Specific Antigen (PSA) Response in Metastatic Hormone-Sensitive Prostate Cancer

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