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03 January 2023: Clinical Research

Analysis of Serum Inflammatory Markers in Infants Under 6 Months of Age with Non-Syndromic Moderate and Severe Hearing Loss Associated with Gene Mutations

Xingang Zhang 1ABE , Zhaoxin Ma 2DF , Jishan Zheng 3CEF , Huiqing Xu 3BC , Jiewen Pan 4EF , Lanqiu Lv 5G*

DOI: 10.12659/MSM.938165

Med Sci Monit 2023; 29:e938165

Table 3 Results of the t test performed to examine differences in expression of inflammatory markers between genders and the severity of hearing loss.

SampleParameterTdofAlternativep-valCI 95%Cohen-dBF10PowerSignificant
Cohort 1A12.2611.88Two-sided0.04[0.04, 2.54]
B12.7111.57Two-sided0.02[0.44, 4.09]1.254.700.90Yes
C1−0.8927.61Two-sided0.38[−112.59, 44.26]0.280.4680.12No
D10.8919.07Two-sided0.38[−72.32, 180.02]0.350.4680.15No
E10.3022.36Two-sided0.77[−3.77, 5.04]0.110.3590.06No
F1−0.6318.92Two-sided0.54[−11.3, 6.09]0.180.4030.08No
G10.5614.84Two-sided0.59[−5.39, 9.2]0.240.390.09No
Cohort 2A2−1.7417.51Two-sided0.10[−0.91, 0.09]0.661.0610.41No
B20.5425.84Two-sided0.59[−0.57, 0.98]0.200.3890.08No
C2−0.3226.99Two-sided0.75[−2.1, 1.54]0.120.360.06No
D2−2.6816.02Two-sided0.02[−3.82, −0.45]1.024.340.76Yes
E2−0.9120.27Two-sided0.38[−6.72, 2.65]0.340.480.14No
F2−0.8625.18Two-sided0.40[−1.01, 0.42]0.320.4610.13No
G2−1.3622.77Two-sided0.19[−1.11, 0.23]0.510.6930.26No
Cohort 3A30.7924.79Two-sided0.44[−0.61, 1.37]0.300.4420.12No
B3−0.2625.06Two-sided0.80[−0.74, 0.58]0.090.360.06No
C31.5515.96Two-sided0.14[−0.66, 4.24]0.620.840.36No
D3−0.8125.65Two-sided0.43[−2.44, 1.06]0.290.4480.12No
E30.2122.45Two-sided0.84[−1.27, 1.55]0.080.3560.05No
F31.2325.38Two-sided0.23[−0.52, 2.05]0.460.6160.22No
G31.2612.15Two-sided0.23[−4.68, 17.47]0.520.6290.27No
A – IL-2; B – IL-4; C – IL-6; D – IL-10; E – IL-17A; F – α-TNF; G – γ-IFN.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750