Analysis of Serum Inflammatory Markers in Infants Under 6 Months of Age with Non-Syndromic Moderate and Severe Hearing Loss Associated with GJB2 Gene Mutations

03 January 2023: Clinical Research

Analysis of Serum Inflammatory Markers in Infants Under 6 Months of Age with Non-Syndromic Moderate and Severe Hearing Loss Associated with Gene Mutations

Xingang Zhang ^1ABE , Zhaoxin Ma ^2DF , Jishan Zheng ^3CEF , Huiqing Xu ^3BC , Jiewen Pan ^4EF , Lanqiu Lv ^5G*

DOI: 10.12659/MSM.938165

Med Sci Monit 2023; 29:e938165

Table 5B Linear model results on the relationship among hear loss severity and blood markers.

Severity	Marker	Estimate	Std. error	t value	Pr(>\|t\|)	Signif.	R2
Normal	ln_a	−0.089	0.182	−0.488	0.627	ns	0.088
Moderate	ln_a	−0.739	0.256	−2.892	0.005		0.088
Severe	ln_a	−0.414	0.254	−1.633	0.106	ns	0.088
Normal	ln_b	−0.182	0.187	−0.971	0.334	ns	0.038
Moderate	ln_b	−0.441	0.262	−1.683	0.096	ns	0.038
Severe	ln_b	−0.391	0.26	−1.504	0.136	ns	0.038
Normal	ln_c	1.048	0.189	5.551	0.000		0.569
Moderate	ln_c	−0.232	0.265	−0.875	0.384	ns	0.569
Severe	ln_c	2.29	0.263	8.714	0.000		0.569
Normal	ln_d	1.075	0.206	5.207	0.000		0.528
Moderate	ln_d	−0.645	0.289	−2.23	0.028		0.528
Severe	ln_d	2.043	0.287	7.114	0.000		0.528
Normal	ln_e	−0.568	0.241	−2.355	0.021		0.152
Moderate	ln_e	1.288	0.338	3.806	0.000		0.152
Severe	ln_e	0.962	0.336	2.866	0.005		0.152
Normal	ln_f	0.04	0.215	0.188	0.851	ns	0.012
Moderate	ln_f	−0.252	0.301	−0.837	0.405	ns	0.012
Severe	ln_f	0.025	0.299	0.084	0.933	ns	0.012
Normal	ln_g	0.372	0.227	1.639	0.105	ns	0.062
Moderate	ln_g	−0.629	0.318	−1.978	0.051	ns	0.062
Severe	ln_g	0.044	0.315	0.14	0.889	ns	0.062