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02 December 2022 : Review article  

Narrative Review of Noninvasive Brain Stimulation in Stroke Rehabilitation

Qian-ru Shen1AEF, Meng-ting Hu1EF, Wei Feng1A, Kun-Peng Li1AEFG*, Wu Wang ORCID logo2AG

DOI: 10.12659/MSM.938298

Med Sci Monit 2022; 28:e938298

Table 3 Summary of clinical studies on post-stroke patients using tACS.

StudyNo.Targeted lesionStudy designFrequencyPeak current intensityLocationScheduleFollow-upOutcomes
Gall et al, 2015 []68 20 (20)Unilateral occipital strokeRCT30 Hz1.5 mAFrontal pole midline point20 min daily for 10 days2 monthsVisual field change positively
Wu et al, 2016 []66 60 (30)Subacute strokeRCT20 Hz400 μAbilateral mastoids30 min daily for 3 weeksN/ANIHSS and the TCD parameters (MFV, PI) in MCAs, ACAs, and PCAs positive
Räty et al, 2021 []67 9 (9)Hemianopia after chronic strokeRCT5–15 Hz1.5 mABilateral frontal pole30 min during days 1–5 and 40 min during days 6–102 monthsNo difference in the median detection accuracy
NIHSS – NIH Stroke Scale; TCD – Transcranial Doppler; MCA – middle cerebral artery; ACA – anterior cerebral artery; PCA – posterior cerebral artery; MFV – mean flow velocity; PI – pulsatility index.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750