02 December 2022: Review Articles
Narrative Review of Noninvasive Brain Stimulation in Stroke Rehabilitation
Qian-ru Shen 1AEF* , Meng-ting Hu 1EF* , Wei Feng 1A , Kun-Peng Li 1AEFG** , Wu Wang 2AG*DOI: 10.12659/MSM.938298
Med Sci Monit 2022; 28:e938298
Table 4 Summary of clinical studies on post-stroke patients using tFUS.
| Study | No. | Targeted lesion | Study design | Intervention | Frequency | Intensity | Location | Schedule | Follow-up | Outcome |
|---|---|---|---|---|---|---|---|---|---|---|
| Zhou et al, 2017 []198 | 80 (40) | Acute cerebral infarction | RCT | tFUS and acupoint application vs conventional | 800 KHz | 0.75 w/cm | Temporal window on the lesion side | 30 d | N/A | Neurological function deficiency scale positive |
| Wang et al, 2020 []199 | 45 (15) | Stroke | RCT | tFUS vs motor imagery vs conventional | 800 KHz | 1.2 W/cm | Temporal window on the lesion side | 20 min for 4 weeks | N/A | FMA, MBI positive |
| Pu et al, 2021 []200 | 114 (38) | Stroke with upper limb disorder | RCT | tFUS vs motor imagery vs conventional | 800 KHz | 1.2 W/cm | Temporal window on the lesion side | 20 min for 4 weeks | N/A | FMA, MBI positive |
| FMA – Fugl-Meyer Assessment; MBI –Modified Barthel Index. | ||||||||||