09 December 2022: Clinical Research
Neuropsychological Features in Patients with General Paresis of the Insane at an Early Stage
Jun-Hua Gao 12345ABE , Du-Yu Ding 5BC , Yan-Yun Qi 5AB , Yu-Ming Huang 5AE , Jing-Lin Zhang 5ADF , Wei Zhang 1234ACEG*DOI: 10.12659/MSM.938316
Med Sci Monit 2022; 28:e938316
Table 3 Laboratory results in serum and cerebrospinal fluid from asymptomatic neurosyphilis (ANS), neurosyphilis-mild cognitive impairment (MCI), and neurosyphilis-dementia groups.
| ANS | Neurosyphilis-MCI | Neurosyphilis-dementia | F/χ2/H value | P value | |
|---|---|---|---|---|---|
| Serum RPR titer, median (IQR) | 1: 8 (1: 8, 1: 16) | 1: 16 (1: 4, 1: 32) | 1: 16 (1: 8, 1: 64) | 3.011 | 0.222 |
| Serum RPR titer ≥1: 32 (n,%) | 1 (3.6) | 8 (42.1)* | 5 (31.3) | 6.716 | 0.035 |
| CSF RPR positive cases (n,%) | 4 (22.2) | 13 (68.4)* | 9 (60.0) | 8.735 | 0.130 |
| CSF RPR titer ≥1: 8 (n,%) | 0 | 1(5.3)* | 5 (33.3)** | 10.062 | 0.007 |
| CSF WBC count (/mL) | 55 (44, 76) | 11(6,35) | 14 (5, 34) | 0.249 | 0.872 |
| CSF WBC count >5/μL cases (n,%) | 13 (72.2) | 15 (78.9) | 11 (73.3) | 0.254 | 0.881 |
| CSF protein concentration, median (IQR) mg/dL | 38 (24.9, 66) | 42.9 (32, 71) | 44.9 (26, 90.8) | 0.752 | 0.536 |
| CSF protein >45 mg/dL cases (n,%) | 8 (44.4) | 8 (42.1) | 7 (46.9) | 0.071 | 0.965 |
| ANS – asymptomatic neurosyphilis; MCI – mild cognitive impairment. * p ** p | |||||