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09 December 2022: Clinical Research

Neuropsychological Features in Patients with General Paresis of the Insane at an Early Stage

Jun-Hua Gao 12345ABE , Du-Yu Ding 5BC , Yan-Yun Qi 5AB , Yu-Ming Huang 5AE , Jing-Lin Zhang 5ADF , Wei Zhang 1234ACEG*

DOI: 10.12659/MSM.938316

Med Sci Monit 2022; 28:e938316

Table 3 Laboratory results in serum and cerebrospinal fluid from asymptomatic neurosyphilis (ANS), neurosyphilis-mild cognitive impairment (MCI), and neurosyphilis-dementia groups.

ANSNeurosyphilis-MCINeurosyphilis-dementiaF/χ2/H valueP value
Serum RPR titer, median (IQR)1: 8 (1: 8, 1: 16)1: 16 (1: 4, 1: 32)1: 16 (1: 8, 1: 64)3.0110.222
Serum RPR titer ≥1: 32 (n,%)1 (3.6)8 (42.1)* 5 (31.3)6.7160.035
CSF RPR positive cases (n,%)4 (22.2)13 (68.4)* 9 (60.0)8.7350.130
CSF RPR titer ≥1: 8 (n,%)01(5.3)* 5 (33.3)** 10.0620.007
CSF WBC count (/mL)55 (44, 76)11(6,35)14 (5, 34)0.2490.872
CSF WBC count >5/μL cases (n,%)13 (72.2)15 (78.9)11 (73.3)0.2540.881
CSF protein concentration, median (IQR) mg/dL38 (24.9, 66)42.9 (32, 71)44.9 (26, 90.8)0.7520.536
CSF protein >45 mg/dL cases (n,%)8 (44.4)8 (42.1)7 (46.9)0.0710.965
ANS – asymptomatic neurosyphilis; MCI – mild cognitive impairment.
* p
** p

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750