09 January 2023: Clinical Research
Effects of Electrical Impedance Tomography-Guided Positive End-Expiratory Pressure on Postoperative Cardiopulmonary Exercise Capacity in Elderly Patients: Study Protocol for a Randomized Controlled Trial
Wentao Liu 1BE , Kang Yu 1B , Li Xiao 1B , Danyang Gao 1B , Xiao Liu 1B , Ying Cao 1B , Xiaowan Lin 1B , Lei Liu 2C , Huihui Miao 1AG* , Tianzuo Li 1AE*DOI: 10.12659/MSM.938333
Med Sci Monit 2023; 29:e938333
Table 1 The schedule of enrollment, interventions, and assessments.
| Timepoint | Study period | Close-out | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Enrolment | Allocation | Post-allocation | ||||||||
| Preoperative visit | Before anesthesia | After intubation | During anesthesia | End of surgery | POD1 | POD3 | POD7 | Before hospital discharge | Hospital discharge | |
| Enrollment | ||||||||||
| Eligibility screen | X | |||||||||
| Informed consent | X | |||||||||
| Demographic data | X | |||||||||
| ARISCAT score | X | |||||||||
| Allocation | X | |||||||||
| Interventions | ||||||||||
| Intervention group | X | |||||||||
| Control group | ||||||||||
| Assessments | ||||||||||
| Cardiopulmonary exercise test | X | X | ||||||||
| Respiratory parameters | X | |||||||||
| Electrical impedance tomography | ||||||||||
| Blood gas analysis | X | X | X | X | X | X | ||||
| Hemodynamic variables | ||||||||||
| Incidence of postoperative complications | X | X | X | |||||||
| Adverse events | ||||||||||
| Hospital stay/ Intensive Care Unit stay | X | |||||||||
| POD – postoperative day; ARISCAT – Assess Respiratory Risk in Surgical Patients in Catalonia. | ||||||||||