Single-Center Study in Lithuania to Evaluate the Role of Transthoracic Impedance Cardiography in the Diagnosis and Outcome Evaluation of 301 Patients with Chronic Heart Failure Exacerbation

24 December 2022 : Clinical Research

Andrius Ališauskas^1ABCDEFG*, Albinas Naudžiūnas^1ACDEFG, Saulius Sadauskas

^1ABCDEF, Laima Jankauskienė^1ACDE, Eglė Kalinauskienė^1ACDE, Giedrė Vanagaitė^2BCDE

DOI: 10.12659/MSM.938389

Med Sci Monit 2022; 28:e938389

Background Material and Methods Results Discussion Conclusions References

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Table 7 Univariate and multivariate Cox proportional hazards analysis to identify heart failure patients at risk of cardiac death.

Variable (univariate analysis)	HR (95% CI)	p-value
Age	1.000 (0.987–1.014)	0.972
Gender (Male)	1.101 (0.778–1.559)	0.586
BMI	1.005 (0.978–1.032)	0.726
Heart rate	1.003 (0.996–1.011)	0.408
sBP	0.991 (0.983–0.998)
dBP	0.996 (0.984–1.007)	0.475
Respiratory rate	1.237 (1.161–1.318)
SpO	0.987 (0.958–1.017)	0.399
LVEF	0.938 (0.926–0.950)
LVDd	1.052 (1.034–1.071)
LAD	1.035 (1.022–1.048)
Serum creatinine	1.006 (1.003–1.009)
Serum sodium	0.969 (0.969–1.017)	0.204
Serum potassium	0.930 (0.685–1.313)	0.678
NT-proBNP	1.003 (1.002–1.003)
6MWD	0.990 (0.985–0.994)
SI	0.982 (0.965–0.995)
CO	0.929 (0.849–1.016)	0.109
LCW	0.936 (0.847–1.000)	0.051
LCWI	0.851 (0.723–1.001)	0.052
TFC	1.037 (1.024–1.050)
TFCI	1.058 (1.034–1.082)
STR	1.158 (1.016–1.209)	0.056
^*
Total fluid content ≥36.9 1/kOhm	4.604 (2.701–7.849)
NT-proBNP ≥425.5 pmoL/L	5.104 (3.326–7.832)
LVEF ≤40%	4.942 (2.8256–8.647)
BMI – body mass index; sBP – systolic blood pressure; dBP – diastolic blood pressure; SpO – noninvasively measured oxygen saturation; LVEF – left ventricular ejection fraction; LVDd – left ventricular end-diastolic dimension; LAD – left atrial dimension; NT-proBNP – amino-terminal pro-brain natriuretic peptide; 6MWD – 6-min walk distance; SI – systolic index; CO – cardiac output; LCW – left cardiac work; LCWI – left cardiac work index; STR – systolic time ratio; TFC – thoracic fluid content; TFCI – thoracic fluid content index. ^* Adjusted for age, sex, NYHA class, and body mass index.

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