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24 November 2022: Clinical Research

Single-Center Study in Lithuania to Evaluate the Role of Transthoracic Impedance Cardiography in the Diagnosis and Outcome Evaluation of 301 Patients with Chronic Heart Failure Exacerbation

Andrius Ališauskas 1ABCDEFG* , Albinas Naudžiūnas 1ACDEFG , Saulius Sadauskas 1ABCDEF , Laima Jankauskienė 1ACDE , Eglė Kalinauskienė 1ACDE , Giedrė Vanagaitė 2BCDE

DOI: 10.12659/MSM.938389

Med Sci Monit 2022; 28:e938389

Table 7 Univariate and multivariate Cox proportional hazards analysis to identify heart failure patients at risk of cardiac death.

Variable (univariate analysis)HR (95% CI)p-value
Age1.000 (0.987–1.014)0.972
Gender (Male)1.101 (0.778–1.559)0.586
BMI1.005 (0.978–1.032)0.726
Heart rate1.003 (0.996–1.011)0.408
sBP0.991 (0.983–0.998)
dBP0.996 (0.984–1.007)0.475
Respiratory rate1.237 (1.161–1.318)
SpO0.987 (0.958–1.017)0.399
LVEF0.938 (0.926–0.950)
LVDd1.052 (1.034–1.071)
LAD1.035 (1.022–1.048)
Serum creatinine1.006 (1.003–1.009)
Serum sodium0.969 (0.969–1.017)0.204
Serum potassium0.930 (0.685–1.313)0.678
NT-proBNP1.003 (1.002–1.003)
6MWD0.990 (0.985–0.994)
SI0.982 (0.965–0.995)
CO0.929 (0.849–1.016)0.109
LCW0.936 (0.847–1.000)0.051
LCWI0.851 (0.723–1.001)0.052
TFC1.037 (1.024–1.050)
TFCI1.058 (1.034–1.082)
STR1.158 (1.016–1.209)0.056
Total fluid content ≥36.9 1/kOhm4.604 (2.701–7.849)
NT-proBNP ≥425.5 pmoL/L5.104 (3.326–7.832)
LVEF ≤40%4.942 (2.8256–8.647)
BMI – body mass index; sBP – systolic blood pressure; dBP – diastolic blood pressure; SpO – noninvasively measured oxygen saturation; LVEF – left ventricular ejection fraction; LVDd – left ventricular end-diastolic dimension; LAD – left atrial dimension; NT-proBNP – amino-terminal pro-brain natriuretic peptide; 6MWD – 6-min walk distance; SI – systolic index; CO – cardiac output; LCW – left cardiac work; LCWI – left cardiac work index; STR – systolic time ratio; TFC – thoracic fluid content; TFCI – thoracic fluid content index.
* Adjusted for age, sex, NYHA class, and body mass index.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750