08 February 2023 : Database Analysis
High SPATA18 Expression and its Diagnostic and Prognostic Value in Clear Cell Renal Cell Carcinoma
Xie Lingui1ACE, Liu Weifeng1BC, Wang Yufei1B, Zhou Yibin1AFG*DOI: 10.12659/MSM.938474
Med Sci Monit 2023; 29:e938474
Table 3 Relationship between SPATA18 mRNA expression and clinical characteristics in ccRCC.
| Characteristic | Variable | Expression of SPATA18 (%) | χ2 | p | |
|---|---|---|---|---|---|
| Low (n=265) | High (n=265) | ||||
| Age | ≤60 | 130 (24.5) | 134 (25.3) | 0.07 | 0.794 |
| >60 | 135 (25.5) | 131 (24.7) | |||
| Gender | Female | 85 (16.0) | 101 (19.1) | 1.86 | 0.172 |
| Male | 180 (34.0) | 164 (30.9) | |||
| Histologic grade | G1 | 7 (1.3) | 7 (1.3) | 34.36 | <0.001 |
| G2 | 90 (17.2) | 137 (26.2) | |||
| G3 | 103 (19.7) | 103 (19.7) | |||
| G4 | 59 (11.3) | 16 (3.1) | |||
| Pathologic stage | Stage I | 103 (19.5) | 162 (30.7) | 30.14 | < 0.001 |
| Stage II | 28 (5.3) | 29 (5.5) | |||
| Stage III | 79 (15.0) | 44 (8.3) | |||
| Stage IV | 53 (10.1) | 29 (5.5) | |||
| T stage | T1 | 107 (20.2) | 164 (30.9) | 28.12 | < 0.001 |
| T2 | 37 (7.0) | 32 (6.0) | |||
| T3 | 112 (21.1) | 67 (12.6) | |||
| T4 | 9 (1.7) | 2 (0.4) | |||
| N stage | N0 | 123 (48.2) | 116 (45.5) | 6.45 | 0.011 |
| N1 | 14 (5.5) | 2 (0.8) | |||
| M stage | M0 | 201 (40.4) | 219 (44.0) | 6.31 | 0.012 |
| M1 | 50 (10.0) | 28 (5.6) | |||
| OS event | Alive | 149 (28.1) | 208 (39.2) | 28.87 | <0.001 |
| Dead | 116 (21.9) | 57 (10.8) | |||