08 December 2022 : Clinical Research
Predicting Chemotherapy Resistance in Gestational Trophoblastic Neoplasia: Ratio of Neutrophils, Lymphocytes, Monocytes, and Platelets
Gatot Nyarumenteng Adhipurnawan Winarno1ABCDEF*, Ayu Insafi Mulyantari1ABCDEF, Andi Kurniadi1BD, Dodi Suardi1BD, Zulvayanti Zulvayanti1BD, Nurvita Trianasari2CDOI: 10.12659/MSM.938499
Med Sci Monit 2022; 28:e938499
Table 3 Relationship between pre-chemotherapy ALC, AMC, ANC, NLR, LMR, PLR, FIGO score and chemotherapy outcome in high-risk GTN at Hasan Sadikin Hospital.
| Cut-off point | High risk | p value | Sensitivity | Specificity | PPV | NPV | AUC | |
|---|---|---|---|---|---|---|---|---|
| ChemoresistanceN=29 | ChemosensitiveN=34 | |||||||
| 72.4% | 76.5% | 72.4% | 76.55% | 79.8% | ||||
| >2.6542 | 21 (72.4%) | 8 (23.5%) | ||||||
| ≤2.6542 | 8 (27.6%) | 26 (76.5%) | ||||||
| 55.9% | 75.9% | 73.1% | 59.5% | 69.2% | ||||
| >3.8712 | 19 (55.9%) | 7 (24.1%) | ||||||
| ≤3.8712 | 15 (44.1%) | 22 (75.9%) | ||||||
| 72.4% | 73.5% | 70.0% | 75.8% | 75.5% | ||||
| >192.1746 | 21 (72.4%) | 9 (26.5%) | ||||||
| ≤192.1746 | 8 (27.6%) | 25 (73.5%) | ||||||