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17 February 2023: Clinical Research

EXOC3L1: A Novel Prognostic Biomarker Correlated with Immune Infiltration in Esophageal Squamous Cell Carcinoma

Zhan-Fei Zhang 12ABCDEFG*

DOI: 10.12659/MSM.938512

Med Sci Monit 2023; 29:e938512

Table 2 Univariate and multivariate Cox regression analysis of overall survival in patients with ESCC.

VariablesUnivariate analysisMultivariate analysis
HR (95% CI)pHR (95% CI)p
Age (>60 vs ≤60)1.592 (0.676–3.749)0.288
Gender (Male vs Female)10.030 (1.323–76.071)0.0266.371 (0.780–52.074)0.084
Race (Others vs Asian)1.584 (0.638–3.934)0.322
Smoker (Yes vs No)1.661 (0.620–4.447)0.313
Drinker (Yes vs No)3.087 (0.722–13.204)0.128
BMI (>25 vs ≤25)1.066 (0.434–2.619)0.889
Location (Others vs Mid)0.575 (0.246–1.343)0.201
Grade (G2–G3 vs G1)1.293 (0.434–3.851)0.645
Stage (III–IV vs I–II)3.223 (1.807–5.747)3.056 (1.674–5.582)
EXOC3L1 (High vs Low)4.607 (1.736–12.221)0.0022.992 (1.097–8.163)

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750