17 February 2023 : Database Analysis
EXOC3L1: A Novel Prognostic Biomarker Correlated with Immune Infiltration in Esophageal Squamous Cell Carcinoma
Zhan-Fei Zhang12ABCDEFG*DOI: 10.12659/MSM.938512
Med Sci Monit 2023; 29:e938512
Table 2 Univariate and multivariate Cox regression analysis of overall survival in patients with ESCC.
| Variables | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| HR (95% CI) | p | HR (95% CI) | p | |
| Age (>60 vs ≤60) | 1.592 (0.676–3.749) | 0.288 | ||
| Gender (Male vs Female) | 10.030 (1.323–76.071) | 0.026 | 6.371 (0.780–52.074) | 0.084 |
| Race (Others vs Asian) | 1.584 (0.638–3.934) | 0.322 | ||
| Smoker (Yes vs No) | 1.661 (0.620–4.447) | 0.313 | ||
| Drinker (Yes vs No) | 3.087 (0.722–13.204) | 0.128 | ||
| BMI (>25 vs ≤25) | 1.066 (0.434–2.619) | 0.889 | ||
| Location (Others vs Mid) | 0.575 (0.246–1.343) | 0.201 | ||
| Grade (G2–G3 vs G1) | 1.293 (0.434–3.851) | 0.645 | ||
| Stage (III–IV vs I–II) | 3.223 (1.807–5.747) | <0.001 | 3.056 (1.674–5.582) | |
| EXOC3L1 (High vs Low) | 4.607 (1.736–12.221) | 0.002 | 2.992 (1.097–8.163) | |