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14 February 2023: Database Analysis

Association Between Neutrophil-Lymphocyte Ratio and All-Cause Mortality in Critically Ill Patients with Chronic Obstructive Pulmonary Disease: A Retrospective Cohort Study

Shujie Hao 1ABCDEF , Yamei Yuan 1BDEG , Weidong Ye 2BCD , Xiangming Fang 2AEFG*

DOI: 10.12659/MSM.938554

Med Sci Monit 2023; 29:e938554

Table 2 HRs (95% CIs) for mortality across groups of neutrophil-lymphocyte ratio.

Model I (non-adjusted)Model IIModel III
HR (95% CI)P valueP trendHR (95% CI)P valueP trendHR (95% CI)P valueP trend
 Q11 (Ref)1 (Ref)1 (Ref)
 Q21.48 (1.02~2.14)0.0371.41 (0.98~2.04)0.0681.4 (0.95~2.04)0.085
 Q31.94 (1.37~2.76)1.8 (1.27~2.57)0.0011.51 (1.04~2.18)0.028
 Q42.79 (2~3.9)2.62 (1.87~3.67)1.75 (1.21~2.52)0.003
 Q11 (Ref)1 (Ref)1 (Ref)
 Q21.44 (1.02~2.05)0.041.36 (0.96~1.94)0.0851.36 (0.95~1.96)0.094
 Q31.87 (1.34~2.61)1.72 (1.23~2.41)0.0011.49 (1.05~2.11)
 Q42.69 (1.96~3.69)2.5 (1.82~3.43)1.71 (1.22~2.42)0.002
 Q11 (Ref)1 (Ref)1 (Ref)
 Q21.23 (0.89~1.7)0.2191.17 (0.84~1.62)0.351.19 (0.85~1.67)0.302
 Q31.7 (1.26~2.31)0.0011.57 (1.16~2.14)1.42 (1.03~1.95)
 Q42.36 (1.77~3.15)2.19 (1.64~2.93)1.59 (1.16~2.19)0.004
HR – hazard ratio; CI – confidence interval. Models were derived from Cox regression models. non-adjusted. adjusted for: age; sex; race. adjusted for: age; sex; race; diabetes; hypertension; liver disease; renal disease; malignant cancer; platelets; WBC; anion gap; bicarbonate; BUN; chloride; creatinine; potassium; lactate; heart rate; mbp; respiratory rate; temperature; spo2; glucose; sofa; sapsii.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750