14 February 2023>: Database Analysis
Association Between Neutrophil-Lymphocyte Ratio and All-Cause Mortality in Critically Ill Patients with Chronic Obstructive Pulmonary Disease: A Retrospective Cohort Study
Shujie Hao 1ABCDEF , Yamei Yuan 1BDEG , Weidong Ye 2BCD , Xiangming Fang 2AEFG*DOI: 10.12659/MSM.938554
Med Sci Monit 2023; 29:e938554
Table 2 HRs (95% CIs) for mortality across groups of neutrophil-lymphocyte ratio.
Model I (non-adjusted) | Model II | Model III | |||||||
---|---|---|---|---|---|---|---|---|---|
HR (95% CI) | P value | P trend | HR (95% CI) | P value | P trend | HR (95% CI) | P value | P trend | |
Quartiles | 0.003 | ||||||||
Q1 | 1 (Ref) | 1 (Ref) | 1 (Ref) | ||||||
Q2 | 1.48 (1.02~2.14) | 0.037 | 1.41 (0.98~2.04) | 0.068 | 1.4 (0.95~2.04) | 0.085 | |||
Q3 | 1.94 (1.37~2.76) | 1.8 (1.27~2.57) | 0.001 | 1.51 (1.04~2.18) | 0.028 | ||||
Q4 | 2.79 (2~3.9) | 2.62 (1.87~3.67) | 1.75 (1.21~2.52) | 0.003 | |||||
Quartiles | 0.002 | ||||||||
Q1 | 1 (Ref) | 1 (Ref) | 1 (Ref) | ||||||
Q2 | 1.44 (1.02~2.05) | 0.04 | 1.36 (0.96~1.94) | 0.085 | 1.36 (0.95~1.96) | 0.094 | |||
Q3 | 1.87 (1.34~2.61) | 1.72 (1.23~2.41) | 0.001 | 1.49 (1.05~2.11) | |||||
Q4 | 2.69 (1.96~3.69) | 2.5 (1.82~3.43) | 1.71 (1.22~2.42) | 0.002 | |||||
Quartiles | 0.002 | ||||||||
Q1 | 1 (Ref) | 1 (Ref) | 1 (Ref) | ||||||
Q2 | 1.23 (0.89~1.7) | 0.219 | 1.17 (0.84~1.62) | 0.35 | 1.19 (0.85~1.67) | 0.302 | |||
Q3 | 1.7 (1.26~2.31) | 0.001 | 1.57 (1.16~2.14) | 1.42 (1.03~1.95) | |||||
Q4 | 2.36 (1.77~3.15) | 2.19 (1.64~2.93) | 1.59 (1.16~2.19) | 0.004 | |||||
HR – hazard ratio; CI – confidence interval. Models were derived from Cox regression models. non-adjusted. adjusted for: age; sex; race. adjusted for: age; sex; race; diabetes; hypertension; liver disease; renal disease; malignant cancer; platelets; WBC; anion gap; bicarbonate; BUN; chloride; creatinine; potassium; lactate; heart rate; mbp; respiratory rate; temperature; spo2; glucose; sofa; sapsii. |