23 December 2022: Clinical Research
Factors for In-Hospital Mortality in 145 Male Patients with Fournier’s Gangrene: A 10-Year Observational Study from a Single Tertiary Referral Center in Indonesia
Yufi Aulia Azmi 12ABCDEF , Firas Farisi Alkaff 34ACDEF , Abdul Khairul Rizki Purba 24ACDEF* , Johan Renaldo 1BCEF , Niwanda Yogiswara 1BCEF , Maarten J. Postma 24567DEFDOI: 10.12659/MSM.938578
Med Sci Monit 2022; 28:e938578
Table 1 Clinical characteristics of patients with Fournier’s gangrene.
| Variables | Total N=145 | Non-survivors N=38 | Survivors N=107 | P value |
|---|---|---|---|---|
| Age in years, median [IQR0 | 52 [43–61] | 55 [43–61] | 52 [42–60] | 0.257 |
| Length of stay, median [IQR] | 12 [–]5 | 8 [–]4 | 12 [–]7 | |
| Location, n (%) | ||||
| Perineum | 38 (26.2) | 12 (31.6) | 26 (24.3) | 0.381 |
| Scrotum | 84 (57.9) | 23 (60.5) | 61 (57.0) | 0.706 |
| Penoscrotal | 23 (15.9) | 3 (7.9) | 20 (18.7) | 0.118 |
| Diabetes mellitus, n (%) | 90 (62.10) | 29 (76.3) | 61 (57) | |
| Hypertension, n (%) | 37 (25.5) | 9 (23.7) | 28 (26.2) | 0.763 |
| C-reactive protein, median (mg/dL) [IQR] | 10.6 [4.3–21.9] | 9.6 [4.2–26.3] | 11.4 [4.2–18.6] | 1.0 |
| Hemoglobin (g/dL), mean±SD | 11.4±2.1 | 11.2±2.4 | 11.46±2.0 | 0.551 |
| White blood cells (10/μL), median [IQR] | 16.6 [11.6–22.5] | 14.2 [9.6–20.1] | 17.2 [12.2–23.5] | |
| Sodium level (mmol/L), median [IQR] | 135 [132–139] | 135 [133–140] | 135 [131–138] | 0.504 |
| Serum creatinine (mg/dL), median [IQR] | 1.10 [0.80–1.55] | 0.95 [0.71–1.55] | 1.10 [0.80–1.60] | 0.361 |
| Potassium level (mmol/L), median [IQR] | 4.0 [3.6–4.5] | 4.0 [3.7–4.9] | 4.0 [3.5–4.5] | 0.426 |
| Hematocrit (%), median [IQR] | 35.3 [31.2–38.4] | 34.8 [31.2–38.3] | 35.3 [31.1–38.4] | 0.716 |
| Neutrophile (10/μL), median [IQR] | 11.3 [7.8–18.5] | 10.3 [6.8–19.4] | 12.9 [8.2–18.5] | 0.226 |
| Lymphocyte (10/μL), median [IQR] | 1.54 [0.96–2.24] | 1.47 [0.78–2.35] | 1.66 [1.03–2.23] | 0.475 |
| FGSI, median [IQR] | 8.0 [5.0–12.5] | 7.5 [4.8–12.0] | 8.0 [5.0–13.0] | 0.487 |
| IQR – inter-quartile range; SD – standard deviation. In bold, statistically significant results. | ||||