Usefulness of Detecting Brain-Derived Neurotrophic Factor in Intervertebral Disc Degeneration of the Lumbosacral Spine

Rafał Staszkiewicz; Dorian Gładysz; Marcin Gralewski; Kamil Bryś; Michał Garczarek; Marcin Gadzieliński; Wiesław Marcol; Dawid Sobański; Beniamin Oskar Grabarek

doi:10.12659/MSM.938663

16 January 2023 : Clinical Research

Usefulness of Detecting Brain-Derived Neurotrophic Factor in Intervertebral Disc Degeneration of the Lumbosacral Spine

Rafał Staszkiewicz^ABDEF, Dorian Gładysz^ABDEF, Marcin Gralewski^DEF, Kamil Bryś^EF, Michał Garczarek^EF, Marcin Gadzieliński^EF, Wiesław Marcol^E, Dawid Sobański^B, Beniamin Oskar Grabarek^ACDEF

DOI: 10.12659/MSM.938663

Med Sci Monit 2023; 29:e938663

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Table 2 Inclusion and exclusion criteria for the control group.

Inclusion criteria	Exclusion criteria
Up to 45 years of age	Over 45 years of age
No signs of degeneration in the collected material during microscopic examination	Features of degeneration in the collected material during microscopic examination (Hematoxylin & eosin staining)
No neoplastic disease history	Neoplastic disease history
No inflammatory diseases: inflammation of the bone elements of the spine (osteomyelitis); inflammation of the IVD; epidural empyema; shingles; arthritis; inflammatory infiltrates of the rectum; Scheuermann’s disease; Paget’s disease	Spinal disease history
	Inflammatory disease history

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Usefulness of Detecting Brain-Derived Neurotrophic Factor in Intervertebral Disc Degeneration of the Lumbosacral Spine

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