Usefulness of Detecting Brain-Derived Neurotrophic Factor in Intervertebral Disc Degeneration of the Lumbosacral Spine

Rafał Staszkiewicz; Dorian Gładysz; Marcin Gralewski; Kamil Bryś; Michał Garczarek; Marcin Gadzieliński; Wiesław Marcol; Dawid Sobański; Beniamin Oskar Grabarek

doi:10.12659/MSM.938663

16 January 2023 : Clinical Research

Usefulness of Detecting Brain-Derived Neurotrophic Factor in Intervertebral Disc Degeneration of the Lumbosacral Spine

Rafał Staszkiewicz^ABDEF, Dorian Gładysz^ABDEF, Marcin Gralewski^DEF, Kamil Bryś^EF, Michał Garczarek^EF, Marcin Gadzieliński^EF, Wiesław Marcol^E, Dawid Sobański^B, Beniamin Oskar Grabarek^ACDEF

DOI: 10.12659/MSM.938663

Med Sci Monit 2023; 29:e938663

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Table 3 Number of BDNF-positive fibers/1 mm2 and their concentration in the study and control group.

BDNF-positive nerve fibers	Study group		Control group		p-value
BDNF-positive nerve fibers	Mean±SD	95% CI	Mean±SD	95% CI	p-value
Number/1 mm	58.99±215.82	0, 130.95	30.70±54.14	12.65, 48.75	0.442
Concentration [pg/mg]	17.91±19.58	7.48, 28.34	3.17±20.88	1.16, 5.17	<0.001
BDNF – brain-derived neurotrophic factor; 95% CI – 95% confidence interval; SD – standard deviation; -value obtained by Student’s -test.

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Usefulness of Detecting Brain-Derived Neurotrophic Factor in Intervertebral Disc Degeneration of the Lumbosacral Spine

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