16 January 2023 : Clinical Research
Usefulness of Detecting Brain-Derived Neurotrophic Factor in Intervertebral Disc Degeneration of the Lumbosacral Spine
Rafał StaszkiewiczABDEF, Dorian GładyszABDEF, Marcin GralewskiDEF, Kamil BryśEF, Michał GarczarekEF, Marcin GadzielińskiEF, Wiesław MarcolE, Dawid SobańskiB, Beniamin Oskar GrabarekACDEFDOI: 10.12659/MSM.938663
Med Sci Monit 2023; 29:e938663
Table 4 Number of BDNF-positive fibers/1 mm2 and their concentration according to pain intensity.
| Degree of pain intensity | Number of BDNF-positive nerve fibers/1 mm2 | p-value | Concentration of BDNF [pg/mg] | p-value | ||
|---|---|---|---|---|---|---|
| Mean±SD | 95% CI | Mean±SD | 95 %CI | |||
| 2 | 0 | – | 0.359 | 0 | – | 0.706 |
| 3 | 22.27±38.58 | 0, 118.10 | 0 | – | ||
| 4 | 0 | – | 33.52±32.40 | 0, 85.08 | ||
| 5 | 38.97±77.95 | 0, 160.01 | 9.95±4.82 | 0.98, 17.89 | ||
| 6 | 4.45±14.09 | 5.62, 14.53 | 20.58±12.45 | 0.77, 40.39 | ||
| 7 | 11.14±22.27 | 0, 46.58 | 8.89±5.03 | 1.22, 15.09 | ||
| 8 | 22.28±36.39 | 0, 48.29 | 7.52±4.59 | 0, 18.91 | ||
| 9 | 0 | – | 26.08±15.65 | 4.99, 23.12 | ||
| 10 | 77.95±110.23 | 0, 1068.41 | 2.68±1.34 | 1.90, 4.09 | ||
| BDNF – brain-derived neurotrophic factor; 95% CI – 95% confidence interval; SD – standard deviation; -value obtained by one-way ANOVA. | ||||||