Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

07 December 2022 : Clinical Research  

A Prospective Questionnaire-Based Study to Evaluate Factors Affecting the Decision to Receive COVID-19 Vaccination in 267 Patients with Inflammatory Bowel Disease in Poland

Michał Łodyga ORCID logo12ABCDEF*, Katarzyna Maciejewska ORCID logo1ABCDF, Grażyna Rydzewska ORCID logo13ADFG

DOI: 10.12659/MSM.938665

Med Sci Monit 2022; 28:e938665

Table 5 Analyses of relationships between vaccination and selected variables.

VariableNot vaccinatedVaccinatedMD/OR 95% CIp
Me (Q1; Q3)/n (%)
Group
Ulcerative colitis29 (37.7)78 (41.1)0.87 (0.50; 1.49)0.708
Crohn’s disease48 (62.3)112 (58.9)
Duration of disease (years)11.0011.00 (6.00; 14.00)0.00 (−2.00; 2.00)0.813**
Medication used
Mesalamine57 (77.0)146 (78.1)1.06 (0.56; 2.02)0.985
Sulfasalazine6 (8.1)15 (8.0)0.99 (0.37; 2.65)>0.999
Steroids25 (33.8)37 (19.8)0.48 (0.27; 0.88)0.026
Thiopurines40 (54.1)102 (54.5)1.02 (0.59; 1.75)>0.999
Methotrexate, cyclosporine1 (1.4)7 (3.7)2.84 (0.34; 23.48)0.447*
Infliximab, vedolizumab, adalimumab, ustekinumab49 (66.2)108 (57.8)0.70 (0.40; 1.22)0.263
Tofacitinib2 (2.7)8 (4.3)1.61 (0.33; 7.76)0.730*
Other0 (0.0)1 (0.5)>0.999*
Surgical interventions28 (36.4)63 (33.2)0.87 (0.50; 1.51)0.720
Number of operations2.00 (1.00; 3.50)2.00 (1.00; 3.00)0.00 (>−0.01; 1.00)0.931**
Comorbidities16 (21.3)72 (38.1)1.33 (0.76; 2.35)0.392
A history of COVID-1928 (36.8)32 (16.9)0.35 (0.19; 0.64)0.001
Severity of infection
Asymptomatic1 (3.6)1 (3.1)0.158*
Light15 (53.6)11 (34.4)
Medium11 (39.3)20 (62.5)
Severe1 (3.6)0 (0.0)
COVID-19 history among family29 (38.2)48 (25.5)0.56 (0.32; 0.98)0.058
Severity of infection
Asymptomatic1 (3.6)5 (10.6)0.302*
Light7 (25.0)18 (38.3)
Medium18 (64.3)22 (46.8)
Severe2 (7.1)1 (2.1)
Very severe0 (0.0)1 (2.1)
Vaccinations (household members)
No21 (27.6)6 (3.2)<0.001
Yes33 (43.4)169 (90.4)
Not everyone22 (28.9)12 (6.4)
Vaccinations (friends)
No6 (7.9)1 (0.5)<0.001*
Yes17 (22.4)100 (52.9)
Not everyone53 (69.7)88 (46.6)
Influenza vaccination
No67 (90.5)152 (80.4)0.008*
Yes, vaccinated every year0 (0.0)16 (8.5)
Yes, first vaccination in 20200 (0.0)7 (3.7)
Yes, vaccinated every few years7 (9.5)14 (7.4)
Pneumococci vaccination8 (11.0)24 (13.2)1.23 (0.53; 2.89)0.782
Hepatitis B vaccination32 (69.6)105 (71.9)1.12 (0.54; 2.31)0.904
Other vaccinations7 (9.5)37 (19.8)2.36 (1.00; 5.57)0.068
Sex (female)35 (45.5)99 (52.7)1.33 (0.78; 2.27)0.352
Age32.50 (26.00; 38.00)36.00 (28.00; 44.00)3.50 (−1.00; 6.00)0.011
Smoker
No39 (50.6)91 (47.9)0.917
Yes, currently11 (14.3)28 (14.7)
Yes, in past27 (35.1)71 (37.4)
Drink alcohol
No25 (32.9)69 (37.1)0.244
Yes, currently15 (19.7)49 (26.3)
Yes, in past36 (47.4)68 (36.6)
Education
Primary4 (5.3)3 (1.6)0.005*
Secondary35 (46.1)57 (30.0)
Higher37 (48.7)130 (68.4)
Place of residence
Countryside21 (27.3)34 (17.9)<0.001*
City <20 000 inhabitants4 (5.2)13 (6.8)
City 20 000–100 000 inhabitants18 (23.4)30 (15.8)
City 101 000–499 000 inhabitants16 (20.8)13 (6.8)
City >500 000 inhabitants18 (23.4)100 (52.6)
Average income per family member
2000 PLN16 (21.9)22 (11.7)0.008
2000–4000 PLN34 (46.6)79 (42.0)
4000–6000 PLN19 (26.0)47 (25.0)
>6000 PLN4 (5.5)40 (21.3)
Employment
Student9 (12.2)15 (8.0)0.321*
Working40 (54.1)101 (54.0)
Self-employed11 (14.9)30 (16.0)
Farmer1 (1.4)4 (2.1)
Jobless6 (8.1)7 (3.7)
Pensioner6 (8.1)16 (8.6)
Retired1 (1.4)14 (7.5)
N and% are given for qualitative variables, the median with quartiles 1 and 3 are given for quantitative variables. Dependencies between being vaccinated and other qualitative variables were analysed with the chi-square test or Fisher’s exact test.
* Differences in the level of quantitative variables were analysed with the Mann-Whitney U test.
** The odds ratios and median differences were estimated with 95% confidence intervals (OR for 2×2 tables).

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750