04 March 2023 : Clinical Research
Perfusate Neutrophil Gelatinase-Associated Lipocalin, Kidney Injury Molecular-1, Liver-Type Fatty Acid Binding Protein, and Interleukin-18 as Potential Biomarkers to Predict Delayed Graft Function and Long-Term Prognosis in Kidney Transplant Recipients: A Single-Center Retrospective Study
Zejia Sun1AEF, Zihao Gao1ACE, Xin Li1ABC, Xiang Zheng1BD, Wei Wang1AEG*, Peng Qiao1AEFDOI: 10.12659/MSM.938758
Med Sci Monit 2023; 29:e938758
Table 3 Logistic regression of the risk of DGF according to perfusate kidney injury biomarkers (n=102).
| Biomarker | Univariate logistic analyses | Multiple logistic analyses | ||
|---|---|---|---|---|
| OR (95% CI) for DGF | P value | OR (95% CI) for DGF | P value | |
| NGAL (ng/ml) | 1.033 (1.016, 1.051) | <0.001 | 1.204 (1.057, 1.372) | 0.005 |
| L-FABP (ng/ml) | 1.000 (1.000, 1.000) | 0.679 | – | – |
| KIM-1 (ng/ml) | 1.035 (1.016, 1.054) | <0.001 | 1.248 (1.065, 1.463) | 0.006 |
| IL-18 (pg/ml) | 1.001 (0.998, 1.005) | 0.441 | – | – |
| NGAL – neutrophil gelatinase-associated lipocalin; L-FABP – liver-type fatty acid binding protein; KIM-1 – kidney injury molecular-1; IL-18 – interleukin-18; DGF – delayed graft function; OR – odds ratio. | ||||