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04 March 2023: Clinical Research

Perfusate Neutrophil Gelatinase-Associated Lipocalin, Kidney Injury Molecular-1, Liver-Type Fatty Acid Binding Protein, and Interleukin-18 as Potential Biomarkers to Predict Delayed Graft Function and Long-Term Prognosis in Kidney Transplant Recipients: A Single-Center Retrospective Study

Zejia Sun AEF* , Zihao Gao ACE* , Xin Li ABC* , Xiang Zheng BD , Wei Wang AEG#* , Peng Qiao AEF#*

DOI: 10.12659/MSM.938758

Med Sci Monit 2023; 29:e938758

Table 3 Logistic regression of the risk of DGF according to perfusate kidney injury biomarkers (n=102).

BiomarkerUnivariate logistic analysesMultiple logistic analyses
OR (95% CI) for DGFP valueOR (95% CI) for DGFP value
NGAL (ng/ml)1.033 (1.016, 1.051)1.204 (1.057, 1.372)0.005
L-FABP (ng/ml)1.000 (1.000, 1.000)0.679
KIM-1 (ng/ml)1.035 (1.016, 1.054)1.248 (1.065, 1.463)0.006
IL-18 (pg/ml)1.001 (0.998, 1.005)0.441
NGAL – neutrophil gelatinase-associated lipocalin; L-FABP – liver-type fatty acid binding protein; KIM-1 – kidney injury molecular-1; IL-18 – interleukin-18; DGF – delayed graft function; OR – odds ratio.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750