04 March 2023>: Clinical Research
Perfusate Neutrophil Gelatinase-Associated Lipocalin, Kidney Injury Molecular-1, Liver-Type Fatty Acid Binding Protein, and Interleukin-18 as Potential Biomarkers to Predict Delayed Graft Function and Long-Term Prognosis in Kidney Transplant Recipients: A Single-Center Retrospective Study
Zejia Sun AEF* , Zihao Gao ACE* , Xin Li ABC* , Xiang Zheng BD , Wei Wang AEG#* , Peng Qiao AEF#*DOI: 10.12659/MSM.938758
Med Sci Monit 2023; 29:e938758
Table 3 Logistic regression of the risk of DGF according to perfusate kidney injury biomarkers (n=102).
Biomarker | Univariate logistic analyses | Multiple logistic analyses | ||
---|---|---|---|---|
OR (95% CI) for DGF | P value | OR (95% CI) for DGF | P value | |
NGAL (ng/ml) | 1.033 (1.016, 1.051) | 1.204 (1.057, 1.372) | 0.005 | |
L-FABP (ng/ml) | 1.000 (1.000, 1.000) | 0.679 | – | – |
KIM-1 (ng/ml) | 1.035 (1.016, 1.054) | 1.248 (1.065, 1.463) | 0.006 | |
IL-18 (pg/ml) | 1.001 (0.998, 1.005) | 0.441 | – | – |
NGAL – neutrophil gelatinase-associated lipocalin; L-FABP – liver-type fatty acid binding protein; KIM-1 – kidney injury molecular-1; IL-18 – interleukin-18; DGF – delayed graft function; OR – odds ratio. |