Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

06 February 2023 : Database Analysis  

Comparison of Neonatal Morbidity and Mortality Following Spontaneous and Medically Indicated Preterm Births: A Retrospective Population-Based Study Using Data from the Slovenian National Perinatal Information System 2013-2018

Katja Čehovin1DEF, Ajda Gortnar2DEF, Ivan Verdenik3ABCD, Miha Lučovnik34ACDE, Lilijana Kornhauser-Cerar3ACDE, Štefan Grosek356ACDEFG*

DOI: 10.12659/MSM.938941

Med Sci Monit 2023; 29:e938941

Table 2 Neonatal outcomes according to type of preterm birth at GA 22 0/7 to 36 6/7 weeks.

Spontaneous preterm birth N (%)Medically indicated preterm birth N (%)OR (95% CI)*Adjusted OR (95% CI) multivariate analysis**
Neonatal mortality43 (0.7%)23 (0.8%)0.88 [0.53–1.46]0.56 [0.26–1.20]
IVH62 (1.0%)11 (0.4%)2.67 [1.41–5.09]1.01 [0.43–2.33]
cPVL24 (0.4%)10 (0.3%)1.13 [0.54–2.37]0.68 [0.27–1.73]
BPD162 (2.6%)69 (2.3%)1.11 [0.83–1.48]0.81 [0.52–1.26]
NEC41 (0.7%)24 (0.8%)0.80 [0.49–1.33]0.55 [0.27–1.15]
LOS58 (0.9%)16 (0.5%)1.72 [0.99–2.99]1.93 [0.92–4.06]
ROP79 (1.3%)35 (1.2%)1.07 [0.71–1.59]0.33 [0.17–0.63]
Composite neonatal morbidity298 (4.8%)120 (4.1%)1.18 [0.95–1.47]0.76 [0.54–1.08]
IVH – intraventricular hemorrhage (Papile grade 3 or 4); cPVL – cystic periventricular leukomalacia; BPD – bronchopulmonary dysplasia; NEC – necrotizing enterocolitis; LOS – late-onset neonatal sepsis; ROP – retinopathy of prematurity, composite neonatal morbidity defined as any of the conditions above.
* Univariate analysis odds ratio.
** Multivariate analysis odds ratio: Adjusted for small for gestational age (SGA – defined as neonatal weight 37 years, maternal body-mass-index (BMI) >30 kg/m, and in vitro fertilization (IVF).

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750