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20 January 2023: Clinical Research

Monitoring of Autoantibodies Following Autologous Hematopoietic Stem Cell Transplantation in 6 Children with Recently Diagnosed Type 1 Diabetes Mellitus

Alejandro D. Mesples 1ABCDEFG* , Desiree C.T. Cox 23ACDEF , Harriet D. Lundy 1ADE , Sheena Antonio-Collie 1CDG , Charles W. Diggis 1A , Jonathan R.T. Lakey 4ACDEF

DOI: 10.12659/MSM.938979

Med Sci Monit 2023; 29:e938979

Table 2 Variables analyzed in the 6-month follow-up of patients with autoimmune diabetes who received an autologous bone marrow stem cell transplant.

Patient age (years)Ins dose (units)A1c (%)Creatinine (mg/dl)Glyc. control (mg/dl)C peptide (ng/mL)ICA (JDF units)GAD (units/ml)IA2 (units/ml)INS AB (units/ml)
Patient 181060.81.901001018
Patient 272060.91.102091011
Patient 394090.9150–2501325017020
Patient 4101061.11.50198510
Patient 56660.70.7060207
Patient 672060.90871012
ABMHSC – autologous bone marrow hematopoietic stem cells; Ins Dose – insulin daily dose; A1C – glycosylated hemoglobin A1c; Glyc. Control – glycemic control; ICA – islet cell antibodies; IA2– antibodies against islet antigen-related tyrosine phosphatase 2; GAD – glutamic acid-decarboxylase; AIA – antibodies, anti-insulin antibodies.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750