07 January 2023>: Clinical Research
Serum Vitamin D Levels, Disease Activity Score-28 for Rheumatoid Arthritis with C-Reactive Protein (DAS28-CRP), and Cardiac Remodeling Determined by Ventricular Dimensions and Left Atrium Diameter in Patients with Rheumatoid Arthritis: A Prospective Observational Study
Andrea A.P. Batista ABCDEF , Taline Lazzarin ABCDEF* , Filipe W.L. Pereira BC , Antonio Baccaro B , Oswaldo M. Rocha B , Karina L. Narimatsu B , Juli T. Souza B , Pamela N. Modesto B , Silméia Garcia Zanati Bazan B , Suzana E. Tanni CD , Marina P. Okoshi DEG , Bertha F. Polegato E , Sergio A.R. Paiva E , Leonardo Zornoff E , Marcos F. Minicucci ACDE , Paula S. Azevedo ACDEFGDOI: 10.12659/MSM.938989
Med Sci Monit 2023; 29:e938989
Table 3 Demographic and echocardiographic data of 90 patients with rheumatoid arthritis according to left atrium enlargement.
Variable | Left atrium enlargement | p value | |
---|---|---|---|
Yes (n=25) | No (n=65) | ||
Age (years) | 56.2 (±10.1) | 51.6 (±10.8) | 0.064 |
Male, n (%) | 4.0 (16.0) | 12.0 (18.5) | 1.000 |
Hypertension, n (%) | 12.0 (48.0) | 36.0 (55.4) | 0.958 |
Smoking, n (%) | 10.0 (40.0) | 13.0 (20.0) | 0.093 |
LOD (months) | 96.0 (60.0–180.0) | 96 (60.0–180.0) | 0.525 |
Vitamin D (ng/mL) | 26.4 (±9.5) | 32.4 (±10.3) | 0.014 |
DAS28-CRP | 2.7 (2.2–3.0) | 2.6 (2.0–3.4) | 0.978 |
Biological agents, n (%) | 10.0 (40.0) | 36.0 (55.4) | 0.284 |
Corticosteroid, n (%) | 18.0 (72.0) | 46.0 (70.8) | 0.885 |
LVIM (g/m) | 101.8 (±17.4) | 87.3 (±15.3) | |
LVDD (mm) | 47.0 (46.0–48.0) | 46.0 (44.0–48.0) | 0.534 |
RWT | 0.44 (0.38–0.48) | 0.42 (0.38–0.46) | 0.417 |
EF (%) | 70.3 (±3.2) | 69.6 (±2.3) | 0.251 |
DD, n (%) | 14.0 (56.0) | 31.0 (47.7) | 0.638 |
LOD – length of disease; DAS28-CRP – Disease Activity Score-28 for Rheumatoid Arthritis with c-reactive protein; LVMI – left ventricular mass index LVDD – left ventricular diastolic diameter; RWT – relative wall thickness; EF – ejection fraction; DD – diastolic dysfunction. |