07 January 2023 : Clinical Research
Serum Vitamin D Levels, Disease Activity Score-28 for Rheumatoid Arthritis with C-Reactive Protein (DAS28-CRP), and Cardiac Remodeling Determined by Ventricular Dimensions and Left Atrium Diameter in Patients with Rheumatoid Arthritis: A Prospective Observational Study
Andrea A.P. Batista1ABCDEF, Taline Lazzarin1ABCDEF*, Filipe W.L. Pereira1BC, Antonio Baccaro1B, Oswaldo M. Rocha1B, Karina L. Narimatsu2B, Juli T. Souza1B, Pamela N. Modesto2B, Silméia Garcia Zanati Bazan1B, Suzana E. Tanni1CD, Marina P. Okoshi1DEG, Bertha F. Polegato2E, Sergio A.R. Paiva
1E, Leonardo Zornoff1E, Marcos F. Minicucci1ACDE, Paula S. Azevedo1ACDEFG
DOI: 10.12659/MSM.938989
Med Sci Monit 2023; 29:e938989
Table 3 Demographic and echocardiographic data of 90 patients with rheumatoid arthritis according to left atrium enlargement.
| Variable | Left atrium enlargement | p value | |
|---|---|---|---|
| Yes (n=25) | No (n=65) | ||
| Age (years) | 56.2 (±10.1) | 51.6 (±10.8) | 0.064 |
| Male, n (%) | 4.0 (16.0) | 12.0 (18.5) | 1.000 |
| Hypertension, n (%) | 12.0 (48.0) | 36.0 (55.4) | 0.958 |
| Smoking, n (%) | 10.0 (40.0) | 13.0 (20.0) | 0.093 |
| LOD (months) | 96.0 (60.0–180.0) | 96 (60.0–180.0) | 0.525 |
| Vitamin D (ng/mL) | 26.4 (±9.5) | 32.4 (±10.3) | 0.014 |
| DAS28-CRP | 2.7 (2.2–3.0) | 2.6 (2.0–3.4) | 0.978 |
| Biological agents, n (%) | 10.0 (40.0) | 36.0 (55.4) | 0.284 |
| Corticosteroid, n (%) | 18.0 (72.0) | 46.0 (70.8) | 0.885 |
| LVIM (g/m) | 101.8 (±17.4) | 87.3 (±15.3) | <0.001 |
| LVDD (mm) | 47.0 (46.0–48.0) | 46.0 (44.0–48.0) | 0.534 |
| RWT | 0.44 (0.38–0.48) | 0.42 (0.38–0.46) | 0.417 |
| EF (%) | 70.3 (±3.2) | 69.6 (±2.3) | 0.251 |
| DD, n (%) | 14.0 (56.0) | 31.0 (47.7) | 0.638 |
| LOD – length of disease; DAS28-CRP – Disease Activity Score-28 for Rheumatoid Arthritis with c-reactive protein; LVMI – left ventricular mass index LVDD – left ventricular diastolic diameter; RWT – relative wall thickness; EF – ejection fraction; DD – diastolic dysfunction. | |||