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07 January 2023: Clinical Research

Serum Vitamin D Levels, Disease Activity Score-28 for Rheumatoid Arthritis with C-Reactive Protein (DAS28-CRP), and Cardiac Remodeling Determined by Ventricular Dimensions and Left Atrium Diameter in Patients with Rheumatoid Arthritis: A Prospective Observational Study

Andrea A.P. Batista ABCDEF , Taline Lazzarin ABCDEF* , Filipe W.L. Pereira BC , Antonio Baccaro B , Oswaldo M. Rocha B , Karina L. Narimatsu B , Juli T. Souza B , Pamela N. Modesto B , Silméia Garcia Zanati Bazan B , Suzana E. Tanni CD , Marina P. Okoshi DEG , Bertha F. Polegato E , Sergio A.R. Paiva E , Leonardo Zornoff E , Marcos F. Minicucci ACDE , Paula S. Azevedo ACDEFG

DOI: 10.12659/MSM.938989

Med Sci Monit 2023; 29:e938989

Table 3 Demographic and echocardiographic data of 90 patients with rheumatoid arthritis according to left atrium enlargement.

VariableLeft atrium enlargementp value
Yes (n=25)No (n=65)
Age (years)56.2 (±10.1)51.6 (±10.8)0.064
Male, n (%)4.0 (16.0)12.0 (18.5)1.000
Hypertension, n (%)12.0 (48.0)36.0 (55.4)0.958
Smoking, n (%)10.0 (40.0)13.0 (20.0)0.093
LOD (months)96.0 (60.0–180.0)96 (60.0–180.0)0.525
Vitamin D (ng/mL)26.4 (±9.5)32.4 (±10.3)0.014
DAS28-CRP2.7 (2.2–3.0)2.6 (2.0–3.4)0.978
Biological agents, n (%)10.0 (40.0)36.0 (55.4)0.284
Corticosteroid, n (%)18.0 (72.0)46.0 (70.8)0.885
LVIM (g/m)101.8 (±17.4)87.3 (±15.3)
LVDD (mm)47.0 (46.0–48.0)46.0 (44.0–48.0)0.534
RWT0.44 (0.38–0.48)0.42 (0.38–0.46)0.417
EF (%)70.3 (±3.2)69.6 (±2.3)0.251
DD, n (%)14.0 (56.0)31.0 (47.7)0.638
LOD – length of disease; DAS28-CRP – Disease Activity Score-28 for Rheumatoid Arthritis with c-reactive protein; LVMI – left ventricular mass index LVDD – left ventricular diastolic diameter; RWT – relative wall thickness; EF – ejection fraction; DD – diastolic dysfunction.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750