12 April 2023 : Clinical Research
Clinical Evaluation of Continuous Renal Replacement Therapy Combined with Peritoneal Lavage for Severe Acute Pancreatitis: A Retrospective Cohort Study
Wen-zhu Jiang1EF, Hong-jie Zhao2BC, Lu Chen3DF, Xiao-dong Tang3DF, Zhicheng Deng3AE*DOI: 10.12659/MSM.939314
Med Sci Monit 2023; 29:e939314
Table 2 Comparison after the treatment between the 2 groups.
| Combined group (n=26) | CRRT group (n=26) | P | |
|---|---|---|---|
| C-reactive protein (mg/L) | |||
| Treatment day 3 | 152.8±37.2 | 223.4±82.6 | <0.01 |
| Treatment day 7 | 82.2±29.4 | 124.6±51.4 | <0.01 |
| Procalcitonin, ng/mL | |||
| Treatment day 3 | 12.3±6.5 | 18.3±5.2 | <0.01 |
| Treatment day 7 | 2.1±1.1 | 12.5±2.8 | <0.01 |
| Interleukin-6 (pg/mL) | |||
| Treatment day 3 | 627.3±53.9 | 863.4±83.6 | <0.01 |
| Treatment day 7 | 153.8±35.6 | 527.4±37.1 | <0.01 |
| APACHE-II score | |||
| Treatment day 3 | 6.4±2.7 | 8.9±4.1 | <0.05 |
| Treatment day 7 | 3.5±2.3 | 6.2±2.9 | <0.01 |
| Duration of systemic inflammatory response syndrome | 3.5±2.1 | 6.7±2.8 | <0.01 |
| Abdominal distention relief time (hours) | 97.6±7.8 | 125.8±11.9 | <0.01 |
| Abdominal pain relief time (hours) | 67.4±5.3 | 82.3±8.7 | <0.01 |
| Incidence of complication (Clavien-Dindo grade IIIA or above) | 5 (19.2%) | 6 (23.1%) | 0.734 |
| ICU hospital stay (days) | 15.3±1.2 | 20.6±2.4 | <0.01 |
| Hospital stay (days) | 35.2±3.6 | 40.7±5.2 | <0.01 |
| Inpatient hospital costs (1000 dollars) | 56.3±5.7 | 65.7±8.6 | <0.01 |
| Mortality | 1 (3.8%) | 3 (11.4%) | 0.610 |
| Combined group received continuous renal replacement therapy (CCRT) combined with peritoneal lavage. Data are shown as median (range) or number (percentage). | |||