08 July 2023 : Clinical Research
The Triglyceride Glucose (TyG) Index as a Sensible Marker for Identifying Insulin Resistance and Predicting Diabetic Kidney Disease
Hui Fang Li1ABCDEFG*, Xia Miao1B, Ying Li2AGDOI: 10.12659/MSM.939482
Med Sci Monit 2023; 29:e939482
Table 1 Characteristics of patients with type 2 diabetes and with and without DKD.
| Variables | No-DKD Groupn=328 | DKD Groupn=345 | t/z/χ2 | P value |
|---|---|---|---|---|
| Course (years) | 9.958±7.52 | 11.42±8.119* | −2.333 | 0.02 |
| Male (n,%) | 177 (51.0) | 203 (55.9) | 1.722 | 0.189 |
| Age (years) | 63 (55, 70) | 65 (58, 73) | −3.706 | <0.001 |
| TSH | 2.06 (1.32, 3.09) | 1.99 (1.27, 3.125) | −0.172 | 0.863 |
| FT3 | 4.535±1.317 | 4.255±1.336# | 0.521 | 0.006 |
| FT4 | 17.547±4.356 | 17.437±3.847 | 0.737 | 0.727 |
| ALB | 41.3 (39, 44) | 39.6 (36.1, 42.75)# | −5.801 | <0.001 |
| ALT | 17.95 (13.6, 24.2) | 17.7 (12.3, 25.35) | −0.96 | 0.337 |
| GGT | 20.35 (15.425, 28) | 22.9 (16.5, 33.8)# | −2.953 | 0.003 |
| PLT | 235.454±59.752 | 238.334±70.639 | −0.038 | 0.969 |
| Cre | 68.893±20.672 | 84.654±48.59# | −5.166 | <0.001 |
| UA | 316.978±82.975 | 332.416±102.8* | −2.127 | 0.033 |
| LDL-C | 2.822±1.426 | 2.919±1.837 | −0.762 | 0.446 |
| HDL | 1.184±0.331 | 1.124±0.295 | 2.469 | 0.014 |
| TG | 1.677±1.336 | 2.004±2.116* | −2.278 | 0.023 |
| FPB | 8.328±3.71 | 9.572±3.87# | −4.253 | <0.001 |
| TyG | 9.051±0.757 | 9.312±0.831# | −4.26 | <0.001 |
| eGFR | 90.876±15.442 | 81.017±22.702# | −5.641 | <0.001 |
| Data are presented as the mean±SD or median (interquartile range). TSH – thyroid stimulating hormone; FT3 – free triiodothyronine; FT4 – free thyroxine; ALB – albumin; ALT – alanine aminotransferase; GGT – glutamyl aminotransferase; PLT – platelet; Cre – creatinine; HDL – high-density lipoprotein; TG – triglyceride total; UA – uric acid; LDL-C – low-density lipoprotein cholesterol; FPG – fasting plasma glucose; TyG – triglyceride-glucose; eGFR – estimated glomerular filtration rate. * # | ||||