08 July 2023: Clinical Research
The Triglyceride Glucose (TyG) Index as a Sensible Marker for Identifying Insulin Resistance and Predicting Diabetic Kidney Disease
Hui Fang Li 1ABCDEFG* , Xia Miao 1B , Ying Li 2AGDOI: 10.12659/MSM.939482
Med Sci Monit 2023; 29:e939482
Table 3 Univariate and multivariate analyses of patients with type 2 diabetes and with and without diabetic kidney disease.
| Univariate | Multivariate | |||
|---|---|---|---|---|
| OR (95% CI) | P value | OR (95% CI) | P value | |
| TyG | 1.521 (1.247–1.854) | 1.693 (1.022–2.803) | 0.041 | |
| Course (years) | 1.024 (1.004–1.045) | 0.021 | ||
| Age (years) | 1.028 (1.013–1.044) | 1.024 (1.005–1.042) | 0.011 | |
| FT3 | 0.810 (0.688–0.953) | 0.011 | ||
| ALB | 0.891 (0.858–0.925) | 0.888 (0.851–0.927) | ||
| GGT | 1.007 (1.001–1.014) | 0.03 | ||
| HDL | 0.528 (0.315–0.887) | 0.016 | ||
| TG | 1.124 (1.016–1.243) | 0.023 | ||
| FPG | 1.096 (1.049–1.145) | |||
| The triglyceride-glucose (TyG) index was adjusted for age, TSH, FT3, FT4, ALB, ALT, GGT, HDL, and UA. TyG – triglyceride-glucose; FT3 – free triiodothyronine; ALB – albumin; GGT – glutamyl aminotransferase; HDL – high-density lipoprotein; TG – triglyceride total; FPG – fasting plasma glucose; OR – odds ratio; CI – confidence interval. Statistical significance was defined as | ||||