27 July 2023: Clinical Research
Factors Associated with Severe Adenovirus Pneumonia in Children: A Retrospective Study from Guangzhou, China (2017–2019)
Yan Hong ABCDEF , Qiang Wang BCE , Yongling Song BCE , Guangming Liu BCDE , Jun Shen ACDEG*DOI: 10.12659/MSM.939578
Med Sci Monit 2023; 29:e939578
Table 4 Characteristics of children with adenovirus pneumonia according to disease severity.
| Symptoms | Total (n=173) | Mild group (n=117) | Severe group (n=56) | P value | |
|---|---|---|---|---|---|
| Electrolyte disturbances (%) | 0 | 142 (82.08) | 104 (88.89) | 38 (67.86) | 0.001 |
| 1 | 31 (17.92) | 13 (11.11) | 18 (32.14) | ||
| Skin rash (%) | 0 | 164 (94.8) | 111 (64.16) | 53 (94.64) | 1.000 |
| 1 | 9 (5.2) | 6 (5.13) | 3 (5.36) | ||
| Respiratory (%) | |||||
| Respiratory failure (%) | 0 | 164 (94.8) | 116 (99.15) | 48 (85.71) | 0.001 |
| 1 | 9 (5.2) | 1 (0.85) | 8 (14.29) | ||
| Dry and wet rales (%) | 0 | 36 (20.81) | 32 (27.35) | 4 (7.14) | 0.002 |
| 1 | 137 (79.19) | 85 (72.65) | 52 (92.86) | ||
| Bronchiolitis obliterans (%) | 0 | 164 (94.8) | 116 (99.15) | 48 (85.71) | 0.001 |
| 1 | 9 (5.2) | 1 (0.85) | 8 (14.29) | ||
| Complications (%) | 0 | 111 (64.16) | 94 (80.34) | 17 (30.36) | 0.000 |
| 1 | 62 (35.84) | 23 (19.66) | 39 (69.64) | ||
| Diarrhea (%) | 0 | 146 (84.39) | 100 (85.47) | 46 (82.14) | 0.573 |
| 1 | 27 (15.61) | 17 (14.53) | 10 (17.86) | ||
| Seroperitoneum (%) | 0 | 156 (90.17) | 115 (98.29) | 41 (73.21) | 0.000 |
| 1 | 17 (9.83) | 2 (1.71) | 15 (26.79) | ||
| Hepatosplenomegaly (%) | 0 | 136 (78.61) | 88 (75.21) | 48 (85.71) | 0.115 |
| 1 | 37 (21.39) | 29 (24.79) | 8 (14.29) | ||
| Convulsions (%) | 0 | 161 (93.06) | 107 (91.45) | 54 (96.43) | 0.341 |
| 1 | 12 (6.94) | 10 (8.55) | 2 (3.57) | ||
| Poor consciousness (%) | 0 | 158 (91.33) | 109 (93.16) | 49 (87.50) | 0.252 |
| 1 | 15 (8.67) | 8 (6.84) | 7 (12.50) | ||
| Arrhythmia (%) | 0 | 152 (87.86) | 109 (93.16) | 43 (76.79) | 0.002 |
| 1 | 21 (12.14) | 8 (6.84) | 13 (21.21) | ||
| Coagulation disorders (%) | 0 | 166 (95.95) | 116 (99.15) | 50 (89.29) | 0.005 |
| 1 | 7 (4.05) | 1 (0.85) | 6 (10.71) |