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27 July 2023: Clinical Research

Factors Associated with Severe Adenovirus Pneumonia in Children: A Retrospective Study from Guangzhou, China (2017–2019)

Yan Hong ABCDEF , Qiang Wang BCE , Yongling Song BCE , Guangming Liu BCDE , Jun Shen ACDEG*

DOI: 10.12659/MSM.939578

Med Sci Monit 2023; 29:e939578

Table 6 The treatment and outcomes of patients between mild and severe group.

VariableTotalMild groupSevere groupP value
Steroid administration (%)0124 (71.68)103 (88.03)21 (37.50)0.000
149 (28.32)14 (11.97)35 (62.50)
Gamma globulin therapy (%)0167 (96.53)114 (97.44)53 (94.64)0.390
16 (3.47)3 (2.56)3 (5.36)
Antibiotics (%)045 (26.01)39 (33.33)6 (10.71)0.002
1128 (73.99)78 (66.67)50 (89.29)
Plasma transfusion (%)0161 (93.06)115 (98.29)46 (82.14)0.000
112 (6.94)2 (1.71)10 (17.86)
Albumin treatment (%)0145 (84.3)114 (97.44)31 (55.36)0.000
127 (15.7)2 (1.71)25 (44.64)
Vasoactive drugs usage (%)0165 (97.06)117 (100.00)49 (87.50)0.000
15 (2.94)0 (0.00)7 (12.50)
Acetylcysteine solution inhalation (%)0101 (58.72)83 (70.94)19 (33.93)0.000
171 (41.28)34 (29.06)37 (66.07)
Oxygen supply (%)0136 (79.07)116 (99.15)21 (37.50)0.000
136 (20.93)1 (0.85)35 (62.50)
Bronchoscopy (%)0119 (72.12)100 (85.47)23 (41.07)0.000
146 (27.88)17 (14.53)33 (58.93)
Admission to ICU (%)0169 (97.69)116 (99.15)53 (94,64)1.000
14 (2.31)1 (0.85)3 (5.36)
Prognosis after treatment (%)013 (7.51)1 (0.85)12 (21.43)0.000
1160 (92.49)116 (99.15)44 (78.57)

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750