Hippocampal Metabolic Alterations and Cognitive Dysfunction in Varicella Zoster Virus Meningitis: A Single-Center Case Series Study

11 May 2023 : Clinical Research

Huili Liu^1ABEF, Jun Wang^1BCDE, Yanrong Yuan^1BCF, Jing Gu^1BCF, Yongxing Yan^1ACDEG*

DOI: 10.12659/MSM.939670

Med Sci Monit 2023; 29:e939670

Background Material and Methods Results Discussion Conclusions References

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Table 3 Comparison of hippocampus magnetic resonance spectroscopy between the 2 groups (mean±SD).

	VZV meningitis group (n=23)	Control group (n=19)	t	P
Left hippocampus
Cho/Cr	1.31±0.68	1.70±0.78	1.73	0.10
NAA/Cr	1.01±0.45	1.63±1.19	2.35	0.02
NAA/Cho	0.89±0.37	1.15±0.92	1.24	0.22
Right hippocampus
Cho/Cr	1.29±0.51	1.65±0.76	1.84	0.07
NAA/Cr	1.29±0.45	1.81±0.90	2.57	0.01
NAA/Cho	1.16±0.75	1.20±0.57	0.21	0.83
VZV – varicella zoster virus; Cho – choline; Cr – creatine; NAA – N-acetylaspartate.

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