Evaluation of the One-Hour ¹³C-Propionate Breath Test in 49 Patients from a Single Center in Japan to Detect Vitamin B₁₂ Deficiency

08 May 2023 : Clinical Research

Yosuke Sasaki

^1ABCDEFG*, Takahiro Sato^1BDF, Tadashi Maeda

^1BDFG, Fumiya Komatsu

^1BCD, Naoyuki Kawagoe^1BC, Tsunehiko Imai

^1ACDF, Tomoyuki Shigeta

^1BF, Naoyasu Kashima

^1B, Yoshihisa Urita

^1ABDFG

DOI: 10.12659/MSM.940238

Med Sci Monit 2023; 29:e940238

Table 2 Comparisons of RRs (%dose/h) from 1-h PBT between patients with normal and low serum VB12 levels.

Time	VB12 deficiency	Normal	P-value

10 min	37.49±20.12	42.51±19.76	0.365
20 min	46.63±16.23	48.34±11.51	0.365
30 min	42.71±10	42.14±8.14	0.824
40 min	36.91±7.63	35.38±8.92	0.495
50 min	31.42±7.69	29.52±6.71	0.351
60 min	27.55±7.81	27.52±14.53	0.992

10 min	31.41±15.42	40.17±20.00	0.126
20 min	40.85±13.97	44.81±10.04	0.126
30 min	40.06±9.31	40.73±8.17	0.816
40 min	36.23±8.40	34.29±9.49	0.503
50 min	31.29±8.69	28.76±6.67	0.341
60 min	27.67±8.92	28.13±17.61	0.912

10 min	55.71±23.19	46.87±19.25	0.473
20 min	63.97±8.20	54.9±11.50	0.473
30 min	50.69±8.12	44.74±7.70	0.199
40 min	38.95±4.77	37.42±7.65	0.615
50 min	31.84±4.04	30.91±6.79	0.724
60 min	27.2±3.35	26.4±5.90	0.718
VB deficiency was defined as serum VB level