Evaluation of the One-Hour ¹³C-Propionate Breath Test in 49 Patients from a Single Center in Japan to Detect Vitamin B₁₂ Deficiency

08 May 2023 : Clinical Research

Yosuke Sasaki

^1ABCDEFG*, Takahiro Sato^1BDF, Tadashi Maeda

^1BDFG, Fumiya Komatsu

^1BCD, Naoyuki Kawagoe^1BC, Tsunehiko Imai

^1ACDF, Tomoyuki Shigeta

^1BF, Naoyasu Kashima

^1B, Yoshihisa Urita

^1ABDFG

DOI: 10.12659/MSM.940238

Med Sci Monit 2023; 29:e940238

Background Material and Methods Results Discussion Conclusions References

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Table 4 Comparisons of RRs (%dose/h) from 1-h PBT between pre- and post- supplementation.

Time	Pre-supplementation	Post-supplementation	P-value
10 min	34.56±24.89	42.23±21.33	0.501
20 min	37.24±17.11	46.93±10.61	0.188
30 min	32.84±7.90	41.93±7.18	0.024^*
40 min	31.1±9.87	34.01±5.20	0.468
50 min	26.34±8.09	29.84±5.65	0.319
60 min	22.67±6.96	35.27±26.92	0.184
Means and standard deviations are listed. Macrocytosis is defined as mean corpuscular volume >100 fL. ^* PBT – C-propionate breath test; RR – C recovery rate.

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