19 June 2023 : Clinical Research
A Case-Control Study of Cognitive Function in Patients with End-Stage Renal Disease Before and After Hemodialysis in Southern Spain
María Mar Sánchez-Fernández1ABCDEF*, María José Fernández-Serrano2ACDEFG, Antonio S. Moreno-Salazar3ADEF, Pedro L. Quirós-Ganga4ABDEF, Gustavo A. Reyes del Paso
5ACDEF
DOI: 10.12659/MSM.940409
Med Sci Monit 2023; 29:e940409
Table 1 Sociodemographic, biochemical, blood pressure, body composition, and treatment characteristics data in end-stage renal disease patients treated with hemodialysis and heathy participants.
| Variables | ESRD-HD (n=43) | HP (n=42) | |||
|---|---|---|---|---|---|
| Mean | SD | Mean | SD | ||
| Age | 51.72 | 9.310 | 51.83 | 6.525 | |
| Years of education | 10.98 | 4.405 | 11.14 | 3.653 | |
| Sex (%) | Male | 81.4 | 69.0 | ||
| Female | 18.6 | 31.0 | |||
| Current months HD | 42.00 | 61.53 | – | – | |
| Previous TX, n (%) | 17 (39.53) | – | – | ||
| Nº TX | 0.44 | 0.59 | – | – | |
| Total months TX | 42.53 | 81.04 | – | – | |
| Total months HD | 58.88 | 70.25 | – | – | |
| Total months PD | 4.00 | 10.46 | – | – | |
| Total months D | 62.88 | 68.32 | – | – | |
| Total months RRT | 105.42 | 114.56 | – | – | |
| Total Kt/v | 1.69 | 0.41 | – | – | |
| Pre-HD hours | 56.56 | 5.34 | – | – | |
| Post-HD hours | 20.84 | 2.83 | – | – | |
| Hours pre-post evaluation | 47.67 | 36.47 | 35.31 | 6.61 | |
| Hypertensive patients, n (%) | 38 (88.37) | – | – | ||
| Systolic blood pressure* | 140.08 | 20.14 | 128.78 | 13.15 | |
| Diabetic patients, n (%) | 3 (6.98) | – | – | ||
| Water%** | 58.42 | 5.52 | 52.67 | 5.13 | |
| BMI* | 25.71 | 3.55 | 27.64 | 3.45 | |
| Dry weight kg* | 70.45 | 14.27 | 80.04 | 13.52 | |
| Hemoglobin g/dL** | 11.74 | 1.46 | 15.18 | 1.12 | |
| Hematocrit%** | 35.17 | 4.55 | 45.26 | 3.14 | |
| Total proteins g/dL | 6.65 | 1.04 | 7.1 | 0.34 | |
| Total cholesterol mg/dL** | 153.51 | 28.74 | 218.38 | 32.38 | |
| Ferritin ng/mL** | 399.49 | 156.45 | 123.56 | 57.98 | |
| Calcium mg/dL | 9.44 | 1.26 | 9.57 | 0.27 | |
| Phosphorus mg/dL* | 4.75 | 1.61 | 3.36 | 0.63 | |
| Sodium mEq/L | 139.52 | 2.56 | 139.96 | 2.34 | |
| Urea mg/dL** | 124.33 | 33.49 | 35.40 | 11.04 | |
| Creatinine mg/dL** | 9.56 | 2.46 | 0.92 | 0.14 | |
| * p ** p ESRD HD – end-stage renal disease treated with hemodialysis; HP – healthy participants; Current months HD – number of months under current hemodialysis treatment; Previous TX, n (%) – total number (and percentage) of patients previously transplanted; Nº TX – total number of previous transplants received; Total months TX – total number of months in transplantation; Total months HD – total number of months treated with hemodialysis; Total months PD – total number of months treated with peritoneal dialysis; Total months D – total number of months treated with dialysis (hemodialysis and/or peritoneal dialysis); Total months RRT – total number of months treated with renal replacement therapy (hemodialysis, peritoneal dialysis, transplantation); Total Kt/V – clearance time per body water volume, calculated with the second-generation Daugirdas formula; Pre-HD hours – hours that had elapsed since the last hemodialysis in evaluation 2; Post-HD hours – hours between the most recent hemodialysis session and the post-hemodialysis evaluation; Hours pre-post evaluation – hours elapsed between pre- and post-evaluations; Water% – percentage of body water; BMI – body mass index; Dry weight – ideal weight of individual with no excess fluid in blood. | |||||