31 July 2023 : Clinical Research
Early Lactate/Albumin and Procalcitonin/Albumin Ratios as Predictors of 28-Day Mortality in ICU-Admitted Sepsis Patients: A Retrospective Cohort Study
Fuxing Li1ABCDEF, Zhiqiang Ye2ABCE, Junqi Zhu1ABC, Shumin Gu1BC, Suqin Peng1BCE, Youling Fang1BCE, Longhua Hu1AEF*, Jianqiu Xiong3ACEFDOI: 10.12659/MSM.940654
Med Sci Monit 2023; 29:e940654
Table 2 ROC analysis of laboratory indexes for predicting the prognosis of individuals with sepsis.
| Index | Univariable | Multivariable | ||||
|---|---|---|---|---|---|---|
| OR | 95% CI | P | OR | 95% CI | P | |
| ALB | 0.90 | 0.85–0.95 | <0.001 | – | – | – |
| PCT | 1.02 | 1.01–1.02 | <0.001 | – | – | – |
| Creatinine | 1.00 | 1.00–1.00 | 0.063 | – | – | – |
| Lactate | 1.30 | 1.15–1.48 | <0.001 | – | – | – |
| PCT/ALB | 3.32 | 2.05–5.42 | <0.001 | 2.34 | 1.30–4.20 | 0.004 |
| Lactate/ALB | 3.34 | 2.01–5.59 | <0.001 | 1.64 | 1.31–2.94 | 0.025 |
| APACHE II | 1.07 | 1.03–1.12 | <0.001 | – | – | – |
| SOFA | 1.58 | 1.41–1.78 | <0.001 | 1.49 | 1.33–1.68 | <0.001 |
| Performance of multivaiate model: Number in dataframe=340, Number in model=340, Missing=0, AIC=326.4, C-statistic=0.838, H&L=Chi-sq(8) 21.93 (=0.005). | ||||||