22 June 2023: Clinical Research
Thiol/Disulfide Homeostasis and Ischemia-Modified Albumin Levels in 61 Patients with Hypercapnia: A Case-Control Study
Selahattin Gürü 1ABCDEFG* , Gültekin Kadı 2AB , Çağdaş Yıldırım 3DE , Şervan Gökhan 3CDF , Ayhan Özhasenekler 3BEF , Meltem Gürü 4EF , Salim Neşelioğlu 5DE , Özcan Erel 5CDOI: 10.12659/MSM.940674
Med Sci Monit 2023; 29:e940674
Table 2 The distribution of blood gas and oxidative stress parameters between the hypercapnic and the control groups.
| Hypercapnia (n=61) | Control (n=61) | pa | |
|---|---|---|---|
| Median (25–75%) | Median (25–75%) | ||
| pH | 7.31 (7.24–7.37) | 7.41 (7.40–7.44) | |
| PCO | 58.0 (52.8–65.2) | 39.2 (36.2–42.4) | |
| Native thiol (μmol/L) | 333.9 (272.2–381.4) | 366.3 (322.7–403.6) | |
| Disulphide (μmol/L) | 15.6 (8.0–21.1) | 15.7 (9.6–28.4) | 0.575 |
| Total thiol (μmol/L) | 362.8 (305.8–414.4) | 390.0 (369.1–440.2) | |
| Disulphide/native thiol | 0.05 (0.03–0.08) | 0.04 (0.03–0.07) | 0.802 |
| Disulphide/total thiol | 0.04 (0.02–0.06) | 0.04 (0.03–0.07) | 0.918 |
| Native thiol/total thiol | 0.92 (0.87–0.95) | 0.93 (0.87–0.95) | 0.719 |
| IMA | 77.5 (72.0–82.2) | 67.7 (64.8–70.7) | |
| n – number of individuals; a Mann-Whitney U Test; PCO – arterial partial pressure of CO; IMA – ischemia-modified albumin. | |||