13 October 2023: Clinical Research
Rising Drug Resistance Among Gram-Negative Pathogens in Bloodstream Infections: A Multicenter Study in Ulanhot, Inner Mongolia (2017–2021)
Yinxia Feng 1AE* , Zhijun Wang 1B* , Zelin Hao 2C , Jinlong Du 3D , Hui Jiang 1F*DOI: 10.12659/MSM.940686
Med Sci Monit 2023; 29:e940686
Table 6 Resistance rates of Klebsiella pneumoniae to antibiotics.
| Anti-bacterial agent | 2017 (n=164) | 2018 (n=186) | 2019 (n=201) | 2020 (n=134) | 2021 (n=193) | χ2 | P value |
|---|---|---|---|---|---|---|---|
| Piperacillin | 39.25 | 44.58 | 45.75 | 42.47 | 38.18 | 1.400 | 0.988 |
| Cefazolin | 39.74 | 41.87 | 37.88 | 36.18 | 39.75 | 0.466 | 0.977 |
| Cefuroxime | 36.56 | 41.93 | 38.95 | 37.59 | 30.26 | 2.979 | 0.561 |
| Ampicillin/sulbactam | 24.17 | 37.94 | 37.27 | 40.55 | 37.17 | 5.280 | 0.260 |
| Compound sulfamethoxazole | 33.25 | 40.56 | 31.76 | 29.64 | 29.69 | 3.028 | 0.553 |
| Amoxicillin/clavulanic acid | 18.66 | 52.27 | 43.45 | 28.53 | 16.11 | 35.994 | |
| Piperacillin/tazobactam | 29.44 | 29.72 | 29.87 | 29.15 | 29.81 | 0.034 | 1.000 |
| Levofloxacin | 28.85 | 28.56 | 28.26 | 28.26 | 27.63 | 0.009 | 1.000 |
| Aztreonam | 24.62 | 32.85 | 23.54 | 23.54 | 22.85 | 2.283 | 0.684 |
| Ciprofloxacin | 29.61 | 26.82 | 21.47 | 21.74 | 27.72 | 2.347 | 0.672 |
| Cefoxitin | 26.23 | 25.86 | 26.12 | 26.12 | 26.86 | 0.012 | 1.000 |
| Cefotaxime | 25.24 | 25.74 | 25.45 | 25.45 | 25.58 | 0.044 | 1.000 |
| Minocycline | 27.57 | 30.18 | 21.48 | 24.36 | 20.16 | 3.221 | 0.522 |
| Ceftriaxone | 25.25 | 24.46 | 23.35 | 24.24 | 25.44 | 0.174 | 0.996 |
| Ceftazidime | 19.54 | 26.95 | 26.22 | 17.55 | 21.33 | 2.939 | 0.568 |
| Cefepime | 23.36 | 29.54 | 22.89 | 15.68 | 15.75 | 6.721 | 0.151 |
| Gentamicin | 15.77 | 20.43 | 12.89 | 16.93 | 12.25 | 2.419 | 0.659 |
| Cefoperazone/sulbactam | 8.55 | 8.85 | 8.74 | 8.15 | 8.37 | 0.110 | 0.999 |
| Data are presented as percentage rate (%). | |||||||