12 August 2023: Clinical Research
Transgastric Jejunostomy (PEG-J) for Continuous Infusion of Levodopa-Carbidopa Intestinal Gel: An Approach for Parkinson’s Disease Treatment
Yusuke Nomoto ABCDEF* , Makoto Furihata ABCDEF , Haruka Hagiwara F , Hirotaka Ishino B , Shintaro Yano D , Hiroki Okawa B , Yoichi Nakatsu B , Kumiko Noda B , Shinjiro Nishi F , Shingo Ogiwara AB , Tsuneo Kitamura D , Taro Osada AGDOI: 10.12659/MSM.941285
Med Sci Monit 2023; 29:e941285
Table 2 Procedure-related adverse events.
| Procedure-related AEs | Events | Rate (%) | Occurrence period | Inevitability |
|---|---|---|---|---|
| Pneumonia | 2 | 4.55 | E/L | Ine/Inc |
| Peritonitis | 1 | 2.27 | L | Ine |
| Gastric ulcer | 1 | 2.27 | L | Ine |
| Hemorrhage | 1 | 2.27 | E | Ine |
| Skin trouble | 1 | 2.27 | L | Ine |
| Organ injury | 0 | 0.00 | NA | NA |
| Pneumoperitoneum | 0 | 0.00 | NA | NA |
| Buried bumper syndrome | 0 | 0.00 | NA | NA |
| Intestinal volvulus | 1 | 2.27 | L | Inc |
| Ileum pulling syndrome | 1 ()# | 2.27 | L | Ine |
| Total | 7 (8) | 15.9 (%) | ||
| # – after the observation period; AE – adverse events; E – early AE; L – late AE; Ine – inevitable AE; Inc. – incidental AE; NA – not applicable. The rate was calculated as the number of events divided by gross procedures (n=44). | ||||