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12 August 2023: Clinical Research

Transgastric Jejunostomy (PEG-J) for Continuous Infusion of Levodopa-Carbidopa Intestinal Gel: An Approach for Parkinson’s Disease Treatment

Yusuke Nomoto ABCDEF* , Makoto Furihata ABCDEF , Haruka Hagiwara F , Hirotaka Ishino B , Shintaro Yano D , Hiroki Okawa B , Yoichi Nakatsu B , Kumiko Noda B , Shinjiro Nishi F , Shingo Ogiwara AB , Tsuneo Kitamura D , Taro Osada AG

DOI: 10.12659/MSM.941285

Med Sci Monit 2023; 29:e941285

Table 6 Outcomes of PEG-J procedures.

General outcomes of PEG-J procedures
Procedure time21.7±12.5 (range: 8–51) min.
Hospital stay27.8±15.8 (range: 13–98) days
Successful rate100.0% (n=44/44 procedures)
Mortality rate0.0% (n=0/44 procedures)
Dropout rate (LCIG)16.3% (n=7/43 patients)
Observation period19 (median) (range: 3–40) months
Procedure-related AEs15.9%
Device-related AEs60.5%
PEG-J – percutaneous endoscopic transgastric jejunostomy; LCIG – levodopa-carbidopa intestinal gel; AE – adverse events. Data are presented as mean±standard deviation.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750