06 August 2023>: Article
Dynamics of Microbiome Changes in the Endometrium and Uterine Cervix during Embryo Implantation: A Comparative Analysis
Anna Bednarska-Czerwińska 123ABCDEF* , Emilia Morawiec 14ABDF , Nikola Zmarzły 3CDEF , Michał Szapski 1B , Justyna Jendrysek 1B , Anika Pecyna 1B , Karolina Zapletał-Pudełko 1B , Weronika Małysiak 1B , Tomasz Sirek 56E , Piotr Ossowski 3F , Aleksandra Łach 3E , Dariusz Boroń 3789D , Paweł Bogdał 3F , Adam Bernet 9F , Damian Strojny 3F , Beniamin Oskar Grabarek 13789AEDOI: 10.12659/MSM.941289
Med Sci Monit 2023; 29:e941289
Table 9 Record profile of patients with regard to the type of microbiome.
Microflora | Normal | Light/moderate dysbiosis | Dysbiosis | p | |
---|---|---|---|---|---|
Age [years] | 35.3±4.6 35 (32–38) | 36.5±5.7 38 (32–40) | 34.6±4.5 35 (33–37) | 0.61 | |
Body weight [kg] | 66.7±12.2 64 (57–75.5) | 66.7±16.2 63 (56.7–70) | 59.8±11.9 62 (50–66) | 0.31 | |
BMI [kg/m] | 24.4±4.5 23.7 (21–27.5) | 25.1±7.2 22.4 (19.8–27.3) | 22.2±4.8 22.9 (19.3–24.4) | 0.39 | |
Infertility duration [years] | 5.1±2.9 4 (3–7) | 6.8±6.5 4 (4–5) | 6±2.6 6 (4–8) | 0.46 | |
BMI | Underweight | 5 (83.3) | 0 (0) | 1 (16.7) | 0.19 |
Normal | 52 (76.5) | 6 (8.8) | 10 (14.7) | ||
Overweight | 24 (88.9) | 3 (11.1) | 0 (0) | ||
Obesity | 12 (85.7) | 1 (7.1) | 1 (7.1) | ||
Place of residence | City | 104 (81.3) | 13 (10.2) | 11 (8.6) | 0.32 |
Village | 41 (83.7) | 2 (4.1) | 6 (12.2) | ||
Age [years] | 35.2±4.4 35 (32–39) | 35.5±4.5 36 (32–40) | 35.6±5.9 35.5 (32–37.5) | 0.97 | |
Body weight [kg] | 66.7±11.8 64 (57–75) | 60.9±11.2 62 (54–66) | 65±15.6 63 (56.7–72) | 0.54 | |
BMI [kg/m] | 24.4±4.4 23.6 (21–27.5) | 20.9±3.2 21 (18.4–23.4) | 24.2±6.4 23.1 (19.5–24.9) | 0.24 | |
Infertility duration [years] | 4.9±2.7 4 (3–6) | 6.7±4.8 5 (4–7) | 6.3±3.9 5 (4–7) | 0.2 | |
BMI | Underweight | 4 (66.7) | 1 (16.7) | 1 (16.7) | 0.003 |
Normal | 48 (70.6) | 3 (4.4) | 17 (25) | ||
Overweight | 27 (100) | 0 (0) | 0 (0) | ||
Obesity | 9 (64.3) | 0 (0) | 5 (35.7) | ||
Place of residence | City | 93 (72.7) | 10 (7.8) | 25 (19.5) | 0.28 |
Village | 37 (75.5) | 1 (2) | 11 (22.5) | ||
Age [years] | 35.6±4.9 36 (32–39) | 33.4±3.3 34 (31–36) | 35±3.9 35.5 (32–38) | 0.23 | |
Body weight [kg] | 66.1±12 63 (57–75) | 62.4±11.3 61 (57–65) | 67±15.4 65 (58–72) | 0.64 | |
BMI [kg/m] | 24.2±4.4 23.2 (20.8–27.5) | 24±5.2 23.1 (21.7–24.9) | 24.3±6.1 23.8 (20.8–24.9) | 0.94 | |
Infertility duration [years] | 4.9±2.6 4 (3–6) | 5.6±3.2 5 (3–8.5) | 6.5±4.6 5 (4–7) | 0.49 | |
BMI | Underweight | 4 (66.7) | 1 (16.7) | 1 (16.7) | 0.08 |
Normal | 45 (66.2) | 5 (7.4) | 18 (26.5) | ||
Overweight | 25 (92.6) | 1 (3.7) | 1 (3.7) | ||
Obesity | 8 (57.1) | 1 (7.1) | 5 (35.7) | ||
Place of residence | City | 99 (77.3) | 11 (8.6) | 18 (14.1) | 0.18 |
Village | 35 (71.4) | 2 (4.1) | 12 (24.5) | ||
BMI – body mass index. X±SD, Me (Q1–Q3) – measurable data presented as mean and standard deviation, median (quartiles 1 and 3); N (%) – non-measurable data presented in number-percentage notation. |