17 September 2023: Clinical Research
Impact of Remimazolam versus Sevoflurane Anesthesia on Cerebral Oxygenation and Intracranial Pressure during Gynecological Laparoscopy with Mild Hypercapnia
Chun Gon Park ABC , Dongchul Lee EF , Wol Seon Jeong CF , Dong Seop Kim EF , Youn Yi Jo ABCDEF** , Hyun Jeong Kwak ABCDEF**DOI: 10.12659/MSM.941315
Med Sci Monit 2023; 29:e941315
Table 3 Data from the Postanesthetic Care Unit.
| Sevoflurane (n=30) | Remimazolam (n=30) | P value | |
|---|---|---|---|
| Length of stay in PACU (min) | 38±20 | 28±12 | 0.023 |
| Mean arterial pressure (mmHg) | 106±17 | 103±12 | 0.507 |
| Heart rate (beats/min) | 72±8 | 77±12 | 0.064 |
| PONV (n) | 4 (13) | 2 (7) | 0.335 |
| Pain (NRS) | 4 [3, 6] | 4 [2, 6] | 0.282 |
| Rescue antiemetics (n) | 4 (13) | 0 (0) | 0.038 |
| Rescue analgesics (n) | 22 (73) | 13 (43) | 0.018 |
| Recue fentanyl dose (μg) | 50 [0, 50] | 0 [0, 50] | 0.016 |
| Values are presented as mean±SD, median [interquatile range] or number of patients (%). PACU – Postanesthetic Care Unit; PONV – postoperative nausea and vomiting; NRS – numerical rating scale (0–10). | |||