17 September 2023 : Clinical Research
Impact of Remimazolam versus Sevoflurane Anesthesia on Cerebral Oxygenation and Intracranial Pressure during Gynecological Laparoscopy with Mild Hypercapnia
Chun Gon Park
1ABC, Dongchul Lee1EF, Wol Seon Jung1CF, Dong Seop Kim1EF, Youn Yi Jo1ABCDEF*, Hyun Jeong Kwak1ABCDEF
DOI: 10.12659/MSM.941315
Med Sci Monit 2023; 29:e941315
Table 3 Data from the Postanesthetic Care Unit.
| Sevoflurane (n=30) | Remimazolam (n=30) | P value | |
|---|---|---|---|
| Length of stay in PACU (min) | 38±20 | 28±12 | 0.023 |
| Mean arterial pressure (mmHg) | 106±17 | 103±12 | 0.507 |
| Heart rate (beats/min) | 72±8 | 77±12 | 0.064 |
| PONV (n) | 4 (13) | 2 (7) | 0.335 |
| Pain (NRS) | 4 [3, 6] | 4 [2, 6] | 0.282 |
| Rescue antiemetics (n) | 4 (13) | 0 (0) | 0.038 |
| Rescue analgesics (n) | 22 (73) | 13 (43) | 0.018 |
| Recue fentanyl dose (μg) | 50 [0, 50] | 0 [0, 50] | 0.016 |
| Values are presented as mean±SD, median [interquatile range] or number of patients (%). PACU – Postanesthetic Care Unit; PONV – postoperative nausea and vomiting; NRS – numerical rating scale (0–10). | |||