17 October 2023: Clinical Research
Time-Dependent Factors Influencing Cardiocerebral Vascular Events in Chronic Hemodialysis Patients: Insights from a Longitudinal Study
Haowen Zhong 1CDE* , Mengbi Zhang 1CD* , Xiaoyan Su 1DG* , Yuqin Qin 2C , Yanhong Lai 1B , Jianhua Chen 1F , Linqing Chen 1BF , Aiqin Cao 1F , Xun Liu 3AG* , Shaohong Li 4AG*DOI: 10.12659/MSM.941553
Med Sci Monit 2023; 29:e941553
Table 2 Time-dependent Cox regression revealed the time-dependent influencing factors of cardiocerebral vascular events (CVCs) on hemodialysis (HD) patients.
| Indexes | Univariate | Multivariate | ||||
|---|---|---|---|---|---|---|
| RR | 95% CI | P | RR | 95% CI | P | |
| HGB (g/L) | 0.981 | 0.969–0.992 | 0.001 | |||
| ALB (g/L) | 0.940 | 0.898–0.985 | 0.009 | |||
| WBC (G/L) | 1.102 | 1.051–1.156 | 0.001 | |||
| CRP (mg/L) | 1.008 | 1.005–1.011 | 0.001 | 1.009 | 1.004–1.013 | 0.001 |
| BFR (mL/min) | 0.989 | 0.981–0.996 | 0.005 | 0.991 | 0.984–0.999 | 0.028 |
| Blood flow rate (BFR) during HD was the independent time-dependent protective factor of CVCs on HD patients. C-reactive protein (CRP) was the independent time-dependent risk factor of CVCs on HD patients. CVCs – cardiocerebral vascular events; HD – hemodialysis; BFR – blood flow rate; HGB – hemoglobin; WBC – white blood cells; CRP – C-reactive protein; ALB – serum albumin. | ||||||