Preoperative Systemic Immune-Inflammatory Index as a Predictive Biomarker for Lower Extremity Deep Vein Thrombosis after Breast Cancer Surgery: Stratified Nursing Intervention to Reduce Incidence

17 December 2023: Clinical Research

Lu Tian ^12345ABCDEF* , Jun Zhu ^5ABDF , Xia Li ^5ACD , Lei Huang ^2346ACDEFG* , Li Tian ^12347ACDEFG

DOI: 10.12659/MSM.942087

Med Sci Monit 2023; 29:e942087

Table 2 Univariate analysis of peripheral blood test results between the LEDVT and non-LEDVT groups.

Item	Total (n=552)	Non-LEDVT (n =506)	LEDVT (n=46)	t/Z	P
WBC count (×10/L)	5.87 (4.96, 6.95)	5.94 (5.00, 6.96)	5.75±1.38	−1.343	0.179
Platelet count (10/l)	253.5 (211.0, 290.0)	253.5 (210.0, 290.0)	280.5±59.2	0.171	0.864
Monocytes count (10/l)	0.40 (0.33, 0.51)	0.40 (0.33, 0.50)	0.39 (0.34, 0.51)	−0.462	0.644
SII	426.1 (305.8, 625.3)	406.5 (290.7, 573.4)	616.3 (407.3, 1243.7)	4.579
Hemoglobin (g/L)	134.0 (124.3, 140.0)	133 (125, 139.5)	133.2±12.2	0.488	0.626
Serum test results
Creatinine (μmol/l)	54 (49, 59)	54 (49, 59)	55.3±9.1	1.138	0.255
Albumin (g/L)	44.1 (41.4, 46.4)	44.3 (41.7, 46.9)	42.8±3.5	−2.179	0.029
ALT (U/L)	15 (11, 20)	15 (11, 20)	16 (12, 22)	1.430	0.153
AST (U/L)	18 (16, 22)	18 (16, 22)	19 (17, 24)	1.887	0.059
ALP (U/L)	78 (64, 91)	76 (64, 90)	86±31	1.559	0.119
GGT (U/L)	18 (14, 26)	18 (14, 26)	22 (15, 27)	1.101	0.271
Tbil (umol/L)	12.1 (9.7, 15.2)	12.1 (9.7, 14.9)	12.2 (10.2, 16.0)	0.436	0.663
Fibrinogen (g/L)	2.53 (2.26, 2.94)	2.52 (2.25, 2.94)	2.59 (2.32, 2.98)	0.761	0.447
D-Dimer (mg/dL)	284.4 (194.5, 380.1)	272.9 (191.0, 356.6)	421.6 (275.4, 583.2)	3.882
AST – aspartate aminotransferase; ALP – alkaline phosphatase; ALT – alanine aminotransferase; GGTγ – glutamyltranspeptidase; LEDVT – deep vein thrombosis of lower extremity; SII – systemic inflammatory index; Tbil – total bilirubin; WBC – white blood cells.