17 December 2023 : Clinical Research
Preoperative Systemic Immune-Inflammatory Index as a Predictive Biomarker for Lower Extremity Deep Vein Thrombosis after Breast Cancer Surgery: Stratified Nursing Intervention to Reduce Incidence
Lu Tian12345ABCDEF, Jun Zhu5ABDF, Xia Li5ACD, Lei Huang
2346ACDEFG*, Li Tian12347ACDEF
DOI: 10.12659/MSM.942087
Med Sci Monit 2023; 29:e942087
Table 3 Univariate analysis of surgical data between the LEDVT and non-LEDVT groups.
| Items | Non-LEDVT (n =506) | LEDVT (n=46) | χ2 | P |
|---|---|---|---|---|
| Surgical type, n (%) | ||||
| Radical mastectomy | 328 (64.8) | 33 (71.7) | 0.892 | 0.345 |
| Breast conserving surgery | 6 (1.2) | 0 (0) | 0.551 | 1.000 |
| Radical mastectomy+LN biopsy | 152 (30.0) | 11 (23.9) | 0.761 | 0.383 |
| Breast conserving+LN biopsy | 20 (4.0) | 2 (4.3) | 0.017 | 0.704 |
| The left side of the tumor, n (%) | 244 (48.2) | 21 (45.7) | 0.112 | 0.738 |
| LN involvement, n (%) | 150 (29.6) | 20 (43.5) | 3.786 | 0.066 |
| Pathology type, n (%) | ||||
| Invasive ductal | 420 (83.0) | 36 (78.3) | 0.660 | 0.416 |
| Ductal/in situ | 30 (5.9) | 5 (10.9) | 1.733 | 0.200 |
| Mucinous | 13 (2.6) | 0 (0) | 1.210 | 0.604 |
| Mixed | 10 (2.0) | 3 (6.5) | 3.789 | 0.086 |
| Others | 33 (6.5) | 2 (4.4) | 0.336 | 0.758 |
| T Stage | 8.147 | 0.043 | ||
| T0/Tis/Tx | 86 (17.0) | 11 (23.9) | ||
| T1 | 198 (39.1) | 21 (45.7) | ||
| T2 | 204 (40.3) | 10 (21.7) | ||
| T3 | 18 (3.6) | 4 (8.7) | ||
| N Stage | 23.847 | <0.001 | ||
| N0 | 356 (70.4) | 24 (52.2) | ||
| N1 | 108 (21.3) | 8 (17.4) | ||
| N2 | 13 (2.6) | 3 (6.5) | ||
| N3 | 29 (5.7) | 11 (23.9) | ||
| Pathology features, n (%) | ||||
| Luminal A | 31 (6.1) | 5 (10.9) | 1.556 | 0.210 |
| Luminal B, HER-2− | 220 (43.5) | 16 (34.8) | 1.303 | 0.254 |
| Luminal B, HER-2+ | 145 (28.7) | 10 (21.7) | 0.999 | 0.318 |
| HER-2 overexpression | 79 (15.7) | 10 (21.7) | 1.170 | 0.279 |
| Triple negative | 31 (6.1) | 5 (10.9) | 1.556 | 0.210 |
| Postoperative chemotherapy, n (%) | 218 (43.1) | 13 (28.3) | 3.807 | 0.061 |
| The time of postoperative DVT (day) | – | 3 (2,4) | – | |
| * Other types include invasive lobular carcinoma, invasive micropapillary carcinoma, Paget’s disease of the breast, etcL. DVT – deep vein thrombosis; HER-2 – human epidermal growth factor receptor-2; LN – lymph node; LEDVT – deep vein thrombosis of lower extremity. | ||||