17 December 2023: Clinical Research
Preoperative Systemic Immune-Inflammatory Index as a Predictive Biomarker for Lower Extremity Deep Vein Thrombosis after Breast Cancer Surgery: Stratified Nursing Intervention to Reduce Incidence
Lu Tian 12345ABCDEF* , Jun Zhu 5ABDF , Xia Li 5ACD , Lei Huang 2346ACDEFG* , Li Tian 12347ACDEFGDOI: 10.12659/MSM.942087
Med Sci Monit 2023; 29:e942087
Table 4 Univariate and multivariate logistic regression of predictors of postoperative LEDVT.
| Variables | Univariate | Multivariate | ||||
|---|---|---|---|---|---|---|
| OR | 95% CI | P | OR | 95% CI | P | |
| Age | 2.24 | 1.08–4.63 | 0.03 | – | – | – |
| BMI | 1.85 | 0.97–3.54 | 0.062 | – | – | – |
| Menopause | 3.08 | 1.46–6.50 | 0.003 | 2.97 | 1.20–7.33 | 0.018 |
| LN involvement | 1.83 | 0.96–3.50 | 0.067 | – | – | – |
| Postoperative therapy | 0.52 | 0.26–1.04 | 0.065 | – | – | – |
| Serum ALB level | 0.56 | 0.25–1.24 | 0.155 | – | – | – |
| Serum AST level | 1.71 | 0.87–3.33 | 0.118 | – | – | – |
| Plasma D-Dimer level | 2.38 | 1.24–4.58 | 0.009 | 3.26 | 1.49–7.10 | |
| SII value | 4.90 | 2.50–9.60 | 6.24 | 2.78–14.00 | ||
| T3 stage | 1.77 | 0.45–7.01 | 0.414 | – | – | – |
| N2 stage | 3.38 | 0.79–14.4 | 0.100 | – | – | – |
| N3 stage | 5.71 | 2.30–14.2 | 3.89 | 1.37–11.10 | 0.011 | |
| ALB – albumin; AST – aspartate aminotransferase; BMI – body mass index; CI – confidence interval; LEDVT – deep vein thrombosis of lower extremity; LN – lymph node; OR – odd ratio; SII – systemic inflammatory index. | ||||||