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14 September 2023: Clinical Research

Predicting Survival Outcomes in Post-Cardiac Arrest Syndrome: The Impact of Combined Sequential Organ Failure Assessment Score and Serum Lactate Measurement

SooHyun Kim 1BCE , HeeWon Yang 1BE , BangShill Rhee 1CE , Hakyoon Song 2DF , HyukHoon Kim 1ABCDEF*

DOI: 10.12659/MSM.942119

Med Sci Monit 2023; 29:e942119

Table 1 Baseline characteristics of the study population.

CharacteristicsDeceased discharged patients (n=202)Survival discharged patients (n=236)P value
Age, years63.12 (±17.14)54.41 (±16.24)
Female77 (38.12)69 (29.24)0.062
Diabetes mellitus73 (36.14)67 (28.39)0.098
Hypertension77 (38.12)93 (39.41)0.499
0.003
Cardiogenic59 (29.20)92 (38.98)
Respiratory34 (16.83)40 (16.95)
Metabolic31 (15.34)16 (6.78)
Toxin-related4 (1.98)6 (2.54)
Anaphylaxis1 (0.96)6 (2.54)
Asphyxia36 (17.82)34 (14.41)
Unspecified37 (18.31)42 (17.80)
Witnessed139 (68.81)181 (76.69)0.179
Bystander CPR138 (68.32)180 (76.27)0.107
AED apply40 (19.80)88 (37.29)
Initial shockable rhythm33 (16.33)80 (33.90)
Presumed cardiogenic arrest59 (29.21)92 (38.98)0.041
No-flow time0.00 (0.00–9.00)0.00 (0.00–5.00)0.002
Total CPR time34.94±17.6221.63±15.01
TTM method0.074
Arctic sun128 (63.37)159 (67.37)
Intravascular14 (6.93)27 (11.44)
Cooling pad60 (29.70)50 (21.19)
0.693
From 32°C to 34°C145 (71.78)173 (73.31)
From 35°C to 37°C57 (28.22)63 (26.69)
Sepsis-related factors
Total SOFA score11.32 (±3.38)9.25 (±2.68)
Cardiovascular system3.54 (±1.51)3.11 (±1.41)
Neurological system3.88 (±0.35)3.69 (±0.51)
Hematologic system0.52 (±0.91)0.28 (±0.57)
Respiratory system2.06 (±1.40)1.42 (±1.31)
Hepatic system0.32 (±0.69)0.10 (±0.37)
Renal system1.18 (±1.26)0.67 (± 1.25)
Lactate, mmol/L10.32 (±4.83)7.24 (±4.42)
CRP, mg/dL0.61 (0.08–4.84)0.29 (0.06–2.67)0.010
Values are presented as number (%), mean (±standard deviation), or median (interquartile range). CPR – cardiopulmonary resuscitation; AED – automatic external defibrillator; TTM – target temperature management; SOFA – sequential organ failure assessment; CRP – c-reactive protein.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750