14 September 2023 : Clinical Research
Predicting Survival Outcomes in Post-Cardiac Arrest Syndrome: The Impact of Combined Sequential Organ Failure Assessment Score and Serum Lactate Measurement
SooHyun Kim1BCE, HeeWon Yang1BE, BangShill Rhee1CE, Hakyoon Song2DF, HyukHoon Kim
1ABCDEF*
DOI: 10.12659/MSM.942119
Med Sci Monit 2023; 29:e942119
Table 2 Logistic regression models for survival outcomes.
| Univariate OR (95% CI) | P value | Multivariable OR (95% CI), Model including SOFA score & lactate level*** | P value | Multivariable OR (95% CI), Model including SOFA score# | P value | Multivariable OR (95% CI), Model including lactate level## | P value | |
|---|---|---|---|---|---|---|---|---|
| Age | 0.98 (0.94–0.99) | <0.001 | 0.98 (0.96–1.00) | 0.091 | 0.98 (0.96–1.00) | 0.159 | 0.97 (0.95–0.99) | 0.012 |
| Initial shockable rhythm | 2.91 (1.82–4.71) | <0.001 | 0.81 (0.25–2.60) | 0.448 | 0.62 (0.16–2.30) | 0.486 | 0.84 (0.21–3.19) | 0.810 |
| Use of AED | 2.40 (1.56–3.73) | <0.001 | 3.51 (1.03–13.04) | 0.049 | 2.89 (0.89–10.00) | 0.082 | 3.39 (1.01–12.30) | 0.052 |
| Cardiogenic etiology | 0.76 (0.64–0.89) | <0.001 | 1.37 (0.59–3.16) | 0.452 | 1.50 (0.66–3.39) | 0.323 | 1.11 (0.49–2.48) | 0.794 |
| No-flow time* | 0.96 (0.93–0.98) | <0.001 | 0.94 (0.90–0.98) | 0.014 | 0.94 (0.90–0.97) | 0.003 | 0.95 (0.92–0.99) | 0.033 |
| Total CPR time** | 0.96 (0.95–0.97) | <0.001 | 0.95 (0.93–0.97) | <0.001 | 0.94 (0.92–0.96) | <0.001 | 0.94 (0.92–0.96) | <0.001 |
| SOFA score | 0.79 (0.73–0.85) | <0.001 | 0.77 (0.6–0.88) | <0.001 | 0.76 (0.67–0.86) | <0.001 | - | - |
| Lactate | 0.86 (0.82–0.90) | <0.001 | 0.85 (0.81–0.94) | 0.002 | - | - | 0.87 (0.81–0.94) | <0.001 |
| AED – automatic external defibrillator; CPR – cardiopulmonary resuscitation; SOFA – sequential organ failure assessment; OR – odds ratio; CI – confidence interval. * No-flow time: time from collapse to resuscitation administration. ** Total CPR time: time from resuscitation to return of spontaneous circulation (BLS time+ACLS time). *** Hosmer-Lemeshow X squared=14.94, df=8, value=0.06, indicating a good model fit. 6 of 10. # Hosmer-Lemeshow X squared=9.48, df=8, value=0.30, indicating a good model fit. ## Hosmer-Lemeshow X squared=8.91, df=8, value=0.35, indicating good model fit. | ||||||||