14 December 2023: Clinical Research
Association of Ischemia-Modified Albumin (IMA) in Saliva, Serum, and Urine with Diagnosis of Chronic Kidney Disease (CKD) in Children: A Case-Control Study
Julita Szulimowska 1ABCDEF , Anna Zalewska 1ACD , Katarzyna Taranta-Janusz 2ABD , Daria Trocka 3C , Małgorzata Żendzian-Piotrowska 4C , Ryszard Tomasiuk 5C , Mateusz Maciejczyk 4ACDEFG*DOI: 10.12659/MSM.942230
Med Sci Monit 2023; 29:e942230
Table 1 Clinical characteristics of children with chronic kidney disease (CKD) and healthy children.
| Control (n=24) | CKD (n=24) | |||||
|---|---|---|---|---|---|---|
| Median | 25% percentile | 75% percentile | Median | 25% percentile | 75% percentile | |
| Age (yrs) | 13.5 | 9.25 | 16.75 | 13.5 | 9.25 | 16.75 |
| eGFR (mL/min/1.73 m | 135.3 | 131.6 | 139.6 | 30.95 | 15.00 | 93.20 |
| Serum Cr (mg/dL) | 3.885 | 3.545 | 4.232 | 1.590 | 9.500 | 4,090 |
| Serum urea (mg/dL) | 17.30 | 15.67 | 19.92 | 65.50 | 29.00 | 134.3 |
| Albuminuria (mg/24 h) | ND | ND | ND | 238.5 | 9.665 | 626.4 |
| Proteinuria (mg/24 h) | ND | ND | ND | 192.5 | 84 | 1049 |
| Hgb (g/dL) | ND | ND | ND | 11.7 | 10.6 | 13 |
| Hct (%) | ND | ND | ND | 33.65 | 31 | 38.53 |
| Fe (ug/dL) | ND | ND | ND | 81 | 56.25 | 90 |
| Ferritin(ng/mL) | ND | ND | ND | 74.56 | 32.23 | 271.5 |
| UIBC (mg/dL) | ND | ND | ND | 221 | 142.5 | 269.5 |
| ALP (U/L) | ND | ND | ND | 194 | 109 | 278 |
| PTH (pg/mL) | ND | ND | ND | 64.2 | 36.1 | 127 |
| Ca (mmol/L) | ND | ND | ND | 2.43 | 2.343 | 2.495 |
| Vit. D (mg/mL) | ND | ND | ND | 16 | 8 | 27 |
| SBP (mmHg) | ND | ND | ND | 116 | 109.3 | 123.8 |
| DBP (mmHg) | ND | ND | ND | 73.5 | 64.5 | 77 |
| ALP – alkaline phosphatase; Ca – calcium ions; DBP – diastolic blood pressure; eGFR – estimated glomerular filtration rate determined with the Schwartz formula; Fe – serum iron; Hgb – hemoglobin; Hct – hematocrit; ND – no data; PTH – parathyroid hormone; SBP – systolic blood pressure; sCr – serum creatinine; UA – uric acid; UIBC – unsaturated iron-binding capacity; Vit. D3 – vitamin D3. | ||||||