Association of Ischemia-Modified Albumin (IMA) in Saliva, Serum, and Urine with Diagnosis of Chronic Kidney Disease (CKD) in Children: A Case-Control Study

14 December 2023 : Clinical Research

Julita Szulimowska

^1ABCDEF, Anna Zalewska^1ACD, Katarzyna Taranta-Janusz

^2ABD, Daria Trocka^3C, Małgorzata Żendzian-Piotrowska

^4C, Ryszard Tomasiuk

^5C, Mateusz Maciejczyk

^4ACDEFG*

DOI: 10.12659/MSM.942230

Med Sci Monit 2023; 29:e942230

Background Material and Methods Results Discussion Conclusions References

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Table 2 Total salivary protein, salivary flow rate, and examinations of oral hygiene and periodontal health.

	Control (n=24)			CKD (n=24)			P-value
	Median	25% percentile	75% percentile	Median	25% percentile	75% percentile	P-value
Total protein, NWS (ug/dL)	1523	1315	2175	794	535	979.5	<0.0001
Total protein, SWS (ug/dL)	1509	1340	1707	1101	466	1544.5	0.0026
Salivary flow rate, NWS (mL/min)	0.48	0.4	0.63	0.28	0.2	0.38	<0.0001
Salivary flow rate, SWS (mL/min)	1.5	1.27	1.7	0.8	0.46	1.02	<0.0001
DMFT	8.5	6	10	9	8	10	NS
dmft	2	2.5	3	2	1	3	NS
SBI	1	0	2	2	0	3	NS
GI	0	0	1	1	0	1.75	NS
API (%)	21			24			NS
The Mann-Whitney U test was used for inter-group comparisons. API – approximal plaque index; DMFT – decayed, missing, and filled permanent teeth; dmft – decayed, missing, and filled primary teeth; GI – Gingival Index; NS – non-significance; NWS – non-stimulated whole saliva; SBI – Sulcus Bleeding Index; SWS – stimulated whole saliva.

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