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09 January 2024: Clinical Research

Impact of Respiratory Viruses and SARS-CoV-2 on Febrile Seizures in Saudi Children: Insights into Etiologies, Gender, and Familial Associations

Saleh Fahad AlFulayyih ACDEF , Sarah Saleh Al Baridi ABEFG , Sara Amer Alomar BFG , Ahmed Nawfal Alshammari BFG , Mohammed Shahab Uddin ACDEF*

DOI: 10.12659/MSM.942478

Med Sci Monit 2024; 30:e942478

Table 1 Baseline characteristics of study participants (N=71).Demographic, clinical, and virological characteristics of 71 children aged 6 months to 5 years who were diagnosed with febrile seizures between 2017 and 2021 at a single center in Saudi Arabia.

VariableCategoryResult
NTotal N=71
Age (median, IQR)19.0 [12.0, 36.0]
Sex (n,%)Male32 (45.1)
Female39 (54.9)
Duration of fever (days; median, IQR)2.0 [1.0, 4.0]
Temperature on admission (°C; median, IQR)37.9 [37.3, 38.9]
Maximum temperature (°C; median, IQR)39.1 [38.9, 39.4]
Family history of seizure (%)Yes25 (35.2)
No46 (64.8)
Length of hospital stay (days; median, IQR)3.0 [2.0, 4.0]
Virus (%)H. rhinovirus/enterovirus17 (23.9)
Influenza A or B19 (26.8)
Adenovirus13 (18.3)
Parainfluenza6 (8.5)
RSV6 (8.5)
Others10 (14.1)
SARSCov2 (%)Yes10 (14.1)
No61 (85.9)
Co-infection (%)Yes20 (28.2)
No51 (71.8)
Lumber puncture (%)Yes17 (23.9)
No54 (76.1)
Seizure type (%)Simple seizure49 (69.0)
Complex seizure22 (31.0)
IQR – interquartile range; RSV – respiratory syncytial virus.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750